Sincalide

Base Information Edit

Chemical Name:Sincalide
CAS No.:25126-32-3
Deprecated CAS:9038-72-6,25345-10-2,89911-55-7,91921-74-3
Molecular Formula:C49H62N10O16S3
Molecular Weight:1143.29
Hs Code.:2933998090
European Community (EC) Number:246-639-0
UNII:M03GIQ7Z6P
DSSTox Substance ID:DTXSID7048617
Nikkaji Number:J236.060H
Wikipedia:Sincalide
Wikidata:Q7521885
NCI Thesaurus Code:C47719
RXCUI:9800
Metabolomics Workbench ID:152182
ChEMBL ID:CHEMBL1121
Mol file:25126-32-3.mol

Synonyms:CCK-8;CCK-OP;Cholecystokinin Octapeptide;Cholecystokinin Pancreozymin C Terminal Octapeptide;Cholecystokinin Pancreozymin C-Terminal Octapeptide;H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2;Kinevac;OP-CCK;Sincalide;SQ 19,844;SQ 19844;SQ-19,844;SQ-19844;SQ19,844;SQ19844;Syncalide

Suppliers and Price of Sincalide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Sincalide Ammonium Salt
500ug
$ 368.00

TRC
SincalideAmmoniumSalt
0.5mg
$ 90.00

Tocris
CCKOctapeptide,sulfated
1
$ 304.00

Sigma-Aldrich
(Tyr[SO3H]27)Cholecystokinin fragment 26-33 Amide ≥97% (HPLC), powder
250 μg
$ 194.00

Sigma-Aldrich
(Tyr[SO3H]27)Cholecystokinin fragment 26-33 Amide ≥97% (HPLC), powder
250ug
$ 186.00

Sigma-Aldrich
(Tyr[SO3H]27)Cholecystokinin fragment 26-33 Amide ≥97% (HPLC), powder
0.5 mg
$ 337.00

Sigma-Aldrich
(Tyr[SO3H]27)Cholecystokinin fragment 26-33 Amide ≥97% (HPLC), powder
.5mg
$ 1990.00

Sigma-Aldrich
(Tyr[SO3H]27)Cholecystokinin fragment 26-33 Amide ≥97% (HPLC), powder
5mg
$ 1910.00

Sigma-Aldrich
(Tyr[SO3H]27)Cholecystokinin fragment 26-33 Amide ≥97% (HPLC), powder
1mg
$ 460.00

Medical Isotopes, Inc.
Sincalide
0.5 mg
$ 585.00

Total 116 raw suppliers

Chemical Property of Sincalide Edit

Chemical Property:

Refractive Index:1.643
PKA:-4.17±0.18(Predicted)
PSA：485.78000
Density:1.441 g/cm³
LogP:3.88830
Storage Temp.:−20°C
Solubility.:0.05 M ammonium hydroxide: 1 mg/mL, clear, colorless
Water Solubility.:Soluble in water 1 g/L at 10°C.
XLogP3:-2.6
Hydrogen Bond Donor Count:13
Hydrogen Bond Acceptor Count:19
Rotatable Bond Count:33
Exact Mass:1142.35073945
Heavy Atom Count:78
Complexity:2180

Purity/Quality:

98% ^*data from raw suppliers

Sincalide Ammonium Salt ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CSCCC(C(=O)NCC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(CC3=CC=CC=C3)C(=O)N)NC(=O)C(CC4=CC=C(C=C4)OS(=O)(=O)O)NC(=O)C(CC(=O)O)N
Isomeric SMILES:CSCC[C@@H](C(=O)NCC(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N)NC(=O)[C@H](CC4=CC=C(C=C4)OS(=O)(=O)O)NC(=O)[C@H](CC(=O)O)N
Recent ClinicalTrials:Thyroid Hormones Homeostasis and Energy Metabolism Changes During Stimulation of Endogenously Secreted Bile Acids (BAs)
Uses Sincalide is used in the biological studies in the preparation of opioid receptors agonistic and CCK receptor antagonistic activity.
Therapeutic Function Choleretic

Technology Process of Sincalide

There total 3 articles about Sincalide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%