O-Methyl-N-<2-(2-methyl-1-benzoyl-3-isoureido)ethyl>thiocarbamate

Base Information

• Chemical Name: O-Methyl-N-<2-(2-methyl-1-benzoyl-3-isoureido)ethyl>thiocarbamate
• CAS No.: 108306-68-9
• Molecular Formula: C₁₃H₁₇N₃O₃S
• Molecular Weight: 295.362
• Mol file: 108306-68-9.mol

Synonyms:O-Methyl-N-<2-(2-methyl-1-benzoyl-3-isoureido)ethyl>thiocarbamate

Chemical Property of O-Methyl-N-<2-(2-methyl-1-benzoyl-3-isoureido)ethyl>thiocarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O-Methyl-N-<2-(2-methyl-1-benzoyl-3-isoureido)ethyl>thiocarbamate

There total 4 articles about O-Methyl-N-<2-(2-methyl-1-benzoyl-3-isoureido)ethyl>thiocarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

methanol (67-56-1) + 3-Benzoylimino-5,6-dihydro-3H<1,2,4>dithiazole> (108306-66-7) → O-Methyl-N-<2-(2-methyl-1-benzoyl-3-isoureido)ethyl>thiocarbamate (108306-68-9)

Guidance literature:

With sodium hydroxide; at 20 ℃; for 1h;

DOI:10.1055/s-1986-33422

Reference yield:

1-(N-Benzoylthiocarbamoyl)-2-imidazolidinethione (108324-95-4) → O-Methyl-N-<2-(2-methyl-1-benzoyl-3-isoureido)ethyl>thiocarbamate (108306-68-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 84 percent / conc. HCl, 30percent H₂O₂ / ethanol / 0.08 h / Heating

2: 80 percent / 25percent aq. NH₄OH / ethanol / 20 °C

3: 76 percent / NaOH / 1 h / 20 °C

With hydrogenchloride; ammonium hydroxide; sodium hydroxide; dihydrogen peroxide; In ethanol;

DOI:10.1055/s-1986-33422

Reference yield:

Benzoyl isothiocyanate (532-55-8) → O-Methyl-N-<2-(2-methyl-1-benzoyl-3-isoureido)ethyl>thiocarbamate (108306-68-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 56 percent / acetone / 4 h / Heating

2: 84 percent / conc. HCl, 30percent H₂O₂ / ethanol / 0.08 h / Heating

3: 80 percent / 25percent aq. NH₄OH / ethanol / 20 °C

4: 76 percent / NaOH / 1 h / 20 °C

With hydrogenchloride; ammonium hydroxide; sodium hydroxide; dihydrogen peroxide; In ethanol; acetone;

DOI:10.1055/s-1986-33422

upstream raw materials:

methanol

3-Benzoylimino-5,6-dihydro-3H<1,2,4>dithiazole>

1-(N-Benzoylthiocarbamoyl)-2-imidazolidinethione

3-Benzoylimino-5,6-dihydro-3H<1,2,4>dithiazole> hydrochloride