2-(5-(2-methoxy-phenoxy)-6-chloro-2-(pyrimidin-2-yl)pyrimidin-4-yloxy)ethanol acetyl ester

Base Information

Chemical Name:2-(5-(2-methoxy-phenoxy)-6-chloro-2-(pyrimidin-2-yl)pyrimidin-4-yloxy)ethanol acetyl ester
CAS No.:1160515-46-7
Molecular Formula:C₁₉H₁₇ClN₄O₅
Molecular Weight:416.821
Hs Code.:

Synonyms:2-(5-(2-methoxy-phenoxy)-6-chloro-2-(pyrimidin-2-yl)pyrimidin-4-yloxy)ethanol acetyl ester

Suppliers and Price of 2-(5-(2-methoxy-phenoxy)-6-chloro-2-(pyrimidin-2-yl)pyrimidin-4-yloxy)ethanol acetyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
BosentanAcetate
500mg
$ 655.00

Total 1 raw suppliers

Chemical Property of 2-(5-(2-methoxy-phenoxy)-6-chloro-2-(pyrimidin-2-yl)pyrimidin-4-yloxy)ethanol acetyl ester

Chemical Property:

Purity/Quality:

90%+ ^*data from raw suppliers

BosentanAcetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Bosentan Acetate is a mixed endothelin receptor antagonist. Used as a vasodilator. Antihypertensive.

Technology Process of 2-(5-(2-methoxy-phenoxy)-6-chloro-2-(pyrimidin-2-yl)pyrimidin-4-yloxy)ethanol acetyl ester

There total 1 articles about 2-(5-(2-methoxy-phenoxy)-6-chloro-2-(pyrimidin-2-yl)pyrimidin-4-yloxy)ethanol acetyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.5%

: 184779-15-5
2-(5-(2-methoxy-phenoxy)-6-chloro-2-(pyrimidin-2-yl)pyrimidin-4-yloxy) ethanol

: 108-24-7
acetic anhydride

: 1160515-46-7
2-(5-(2-methoxy-phenoxy)-6-chloro-2-(pyrimidin-2-yl)pyrimidin-4-yloxy)ethanol acetyl ester

Guidance literature:: With triethylamine; In toluene; at 95 - 100 ℃; for 3 - 4h;

Reference yield: 92.0%

: 1160515-46-7
2-(5-(2-methoxy-phenoxy)-6-chloro-2-(pyrimidin-2-yl)pyrimidin-4-yloxy)ethanol acetyl ester

: 6292-59-7
4-tert-butylbenzenesulphonamide

: 1160515-53-6
2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yloxy]-ethanol acetyl ester

Guidance literature:: 4-tert-butylbenzenesulphonamide; With potassium phosphate; In N,N-dimethyl acetamide; at 75 - 80 ℃; for 0.5h;

2-(5-(2-methoxy-phenoxy)-6-chloro-2-(pyrimidin-2-yl)pyrimidin-4-yloxy)ethanol acetyl ester; In N,N-dimethyl acetamide; at 65 - 70 ℃; for 96h; Product distribution / selectivity;