2,2-dimethyl-propionic acid 2-tert-butoxycarbonylamino-5-(2,2-dimethyl-propionyloxy)-3-o-tolyl-pentyl ester

Base Information

Chemical Name:2,2-dimethyl-propionic acid 2-tert-butoxycarbonylamino-5-(2,2-dimethyl-propionyloxy)-3-o-tolyl-pentyl ester
CAS No.:296264-40-9
Molecular Formula:C₂₇H₄₃NO₆
Molecular Weight:477.642
Hs Code.:

2,2-dimethyl-propionic acid 2-<i>tert</i>-butoxycarbonylamino-5-(2,2-dimethyl-propionyloxy)-3-<i>o</i>-tolyl-pentyl ester

Synonyms:2,2-dimethyl-propionic acid 2-tert-butoxycarbonylamino-5-(2,2-dimethyl-propionyloxy)-3-o-tolyl-pentyl ester

Suppliers and Price of 2,2-dimethyl-propionic acid 2-tert-butoxycarbonylamino-5-(2,2-dimethyl-propionyloxy)-3-o-tolyl-pentyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,2-dimethyl-propionic acid 2-tert-butoxycarbonylamino-5-(2,2-dimethyl-propionyloxy)-3-o-tolyl-pentyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2,2-dimethyl-propionic acid 2-tert-butoxycarbonylamino-5-(2,2-dimethyl-propionyloxy)-3-o-tolyl-pentyl ester

There total 5 articles about 2,2-dimethyl-propionic acid 2-tert-butoxycarbonylamino-5-(2,2-dimethyl-propionyloxy)-3-o-tolyl-pentyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 95-46-5
2-methylphenyl bromide

: 296264-40-9
2,2-dimethyl-propionic acid 2-tert-butoxycarbonylamino-5-(2,2-dimethyl-propionyloxy)-3-o-tolyl-pentyl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: I₂; Mg / tetrahydrofuran / 12 h / 20 °C

1.2: CuI / tetrahydrofuran / 1 h / -78 - -20 °C

1.3: TMSCl / tetrahydrofuran / 12 h / -78 °C

2.1: LiBH₄ / methanol

3.1: PTSA / methanol

4.1: pyridine

With lithium borohydride; iodine; toluene-4-sulfonic acid; magnesium; In tetrahydrofuran; pyridine; methanol; 1.1: Metallation / 1.2: Metallation / 1.3: Grignard reaction / 2.1: Reduction / 3.1: Substitution / 4.1: Acylation;
DOI:10.1016/S0040-4039(00)00765-6

Reference yield:

: 123751-09-7
tert-butyl (4R)-4-[(1E)-3-methoxy-3-oxoprop-1-en-1-yl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

: 296264-40-9
2,2-dimethyl-propionic acid 2-tert-butoxycarbonylamino-5-(2,2-dimethyl-propionyloxy)-3-o-tolyl-pentyl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: I₂; Mg / tetrahydrofuran / 12 h / 20 °C

1.2: CuI / tetrahydrofuran / 1 h / -78 - -20 °C

1.3: TMSCl / tetrahydrofuran / 12 h / -78 °C

2.1: LiBH₄ / methanol

3.1: PTSA / methanol

4.1: pyridine

With lithium borohydride; iodine; toluene-4-sulfonic acid; magnesium; In tetrahydrofuran; pyridine; methanol; 1.1: Metallation / 1.2: Metallation / 1.3: Grignard reaction / 2.1: Reduction / 3.1: Substitution / 4.1: Acylation;
DOI:10.1016/S0040-4039(00)00765-6

Reference yield:

: 4-(3-hydroxy-1-o-tolyl-propyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

: 296264-40-9
2,2-dimethyl-propionic acid 2-tert-butoxycarbonylamino-5-(2,2-dimethyl-propionyloxy)-3-o-tolyl-pentyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: PTSA / methanol

2: pyridine

With toluene-4-sulfonic acid; In pyridine; methanol; 1: Substitution / 2: Acylation;
DOI:10.1016/S0040-4039(00)00765-6