(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl (2R)-2-hydroxy-2-phenylbutanoate

Base Information

Chemical Name:(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl (2R)-2-hydroxy-2-phenylbutanoate
CAS No.:57133-41-2
Molecular Formula:C₂₀H₃₀O₃
Molecular Weight:318.456
Hs Code.:

Synonyms:(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl (2R)-2-hydroxy-2-phenylbutanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl (2R)-2-hydroxy-2-phenylbutanoate

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Technology Process of (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl (2R)-2-hydroxy-2-phenylbutanoate

There total 8 articles about (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl (2R)-2-hydroxy-2-phenylbutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 20229-41-8
l-menthyl phenylglyoxylate

: 557-20-0
diethylzinc

: 57133-41-2
(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl (2R)-2-hydroxy-2-phenylbutanoate

Guidance literature:: l-menthyl phenylglyoxylate; With zinc(II) chloride; In dichloromethane; at 20 ℃; for 0.333333h;

diethylzinc; In hexane; dichloromethane; at -40 ℃; for 6h; optical yield given as %de; diastereoselective reaction;
DOI:10.1002/hlca.201000024