20229-41-8

Basic information

• Product Name: l-menthyl phenylglyoxylate
• Synonyms: l-menthyl phenylglyoxylate
• CAS NO: 20229-41-8
• Molecular Weight: 288.387
• Mol File: 20229-41-8.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: l-menthyl phenylglyoxylate(CAS DataBase Reference)
• NIST Chemistry Reference: l-menthyl phenylglyoxylate(20229-41-8)
• EPA Substance Registry System: l-menthyl phenylglyoxylate(20229-41-8)

Safety Data

• Hazardous Substances Data: 20229-41-8(Hazardous Substances Data)

Upstream product

• 611-73-4 Benzoylformic acid 
• 1603-79-8 phenylglyoxylic acid ethyl ester 
• 2216-51-5 (-)-menthol 
• 103-82-2 phenylacetic acid 
• 26171-78-8 (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 2-phenylacetate 
• 170157-72-9 (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 2-diazo-2-phenylacetate 
• 62977-82-6 benzyl oxo(phenyl)acetate 
• 2085-26-9 bis[(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl]oxalate 
• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 89-78-1 menthol 
• 25726-04-9 phenylglyoxylyl chloride 
• 6405-71-6 Oxo-phenyl-acetic acid 1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl ester 

Downstream Products

• 71065-25-3 2-Hydroxy-2-phenyl-hexanoic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 98510-12-4 3,3-Dimethyl-7-phenyl-2,4,6-trioxa-bicyclo[3.2.0]heptane-7-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 98510-12-4 (S)-3,3-Dimethyl-7-phenyl-2,4,6-trioxa-bicyclo[3.2.0]heptane-7-carboxylic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester 
• 71887-48-4 (S)-3,3,4,4-Tetramethyl-2-phenyl-oxetane-2-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 71887-47-3 (R)-3,3,4,4-Tetramethyl-2-phenyl-oxetane-2-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 71887-47-3 <(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl>-3,3,4,4-tetramethyl-2-phenyl-2-oxetancarboxylat 
• 104049-46-9 2-Hydroxy-6-methyl-2-phenyl-heptanoic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 97291-77-5 <(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl>-3,3,4,4-tetraethoxy-2-phenyl-2-oxetancarboxylat 
• 51667-82-4 phenyl-2 hydroxy-2 methyl-4 pentanoate de (-) menthyle 
• 51667-82-4 phenyl-2 hydroxy-2 methyl-4 pentanoate de (-) menthyle 
• 104049-45-8 phenyl-2 hydroxy-2 octanoate de (-) menthyle 
• 104049-45-8 phenyl-2 hydroxy-2 octanoate de (-) menthyle 
• 88002-12-4 4,4-Diethoxy-2-phenyl-oxetane-2-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 88002-00-0 <(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl>-3,3-diethoxy-2-phenyl-2-oxetancarboxylat 

Relevant articles and documents

Photoinduced Diverse Reactivity of Diazo Compounds with Nitrosoarenes

A diverse reactivity of diazo compounds with nitrosoarene in an oxygen-transfer process and a formal [2 + 2] cycloaddition is reported. Nitosoarene has been exploited as a mild oxygen source to oxidize an in situ generated carbene intermediate under visible-light irradiation. UV-light-mediated in situ generated ketenes react with nitosoarenes to deliver oxazetidine derivatives. These operationally simple processes exemplify a transition-metal-free and catalyst-free protocol to give structurally diverse α-ketoesters or oxazetidines.

Selective Formation of Functionalized α-Quaternary Malononitriles toward 5,5-Disubstituted Pyrrolopyrimidinones

A modular, selective approach to complex α-tertiary substituted malononitriles is reported. The method takes advantage of β-ester-substituted α,α-dinitrile alkenes as highly reactive, chemoselective electrophiles for 1,4-additions with organometallic nucleophiles to produce functionally and sterically dense all-carbon quaternary centers. In the presence of a chiral ester auxiliary bearing an aromatic ring, the 1,4-addition occurs with good to excellent selectivity due to favorable cation-π interactions. The highly functionalized malononitriles represent versatile building blocks and can be applied toward efficient, highly selective syntheses of 5,5-disubstituted pyrrolopyrimidinones.

Asymmetric synthesis of chiral α-keto esters via Grignard addition to oxalates

While enroute to an asymmetric synthesis of the chlorine containing metabolite (-)-cryptosporiopsin an efficient and reliable asymmetric synthesis of chiral α-keto esters was required. These compounds can be conveniently generated in 51-84% yields via Gri