1-(5-bromo-2-methylphenyl)-4-{[2-chloro-3-(trifluoromethyl)phenyl]carbonyl}-2-piperazinone

Base Information

Chemical Name:1-(5-bromo-2-methylphenyl)-4-{[2-chloro-3-(trifluoromethyl)phenyl]carbonyl}-2-piperazinone
CAS No.:1146412-38-5
Molecular Formula:C₁₉H₁₅BrClF₃N₂O₂
Molecular Weight:475.693
Hs Code.:

Synonyms:1-(5-bromo-2-methylphenyl)-4-{[2-chloro-3-(trifluoromethyl)phenyl]carbonyl}-2-piperazinone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(5-bromo-2-methylphenyl)-4-{[2-chloro-3-(trifluoromethyl)phenyl]carbonyl}-2-piperazinone

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Technology Process of 1-(5-bromo-2-methylphenyl)-4-{[2-chloro-3-(trifluoromethyl)phenyl]carbonyl}-2-piperazinone

There total 1 articles about 1-(5-bromo-2-methylphenyl)-4-{[2-chloro-3-(trifluoromethyl)phenyl]carbonyl}-2-piperazinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 850156-39-7
2-chloro-3-(trifluoromethyl)benzoyl chloride

: 1146412-39-6
1-(5-bromo-2-methylphenyl)-2-piperazinone

: 1146412-38-5
1-(5-bromo-2-methylphenyl)-4-{[2-chloro-3-(trifluoromethyl)phenyl]carbonyl}-2-piperazinone

Guidance literature:: With polymer-bound triethylamine; In dichloromethane; at 20 ℃; for 3h; not specified

Reference yield:

: 1146412-38-5
1-(5-bromo-2-methylphenyl)-4-{[2-chloro-3-(trifluoromethyl)phenyl]carbonyl}-2-piperazinone

: 659742-21-9
(6-methylpyridin-3-yl)boronic acid

: 1146412-89-6
4-{[2-chloro-3-(trifluoromethyl)phenyl]carbonyl}-1-[2-methyl-5-(6-methyl-3-pyridinyl)phenyl]-2-piperazinone formate

Guidance literature:: With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; water; at 100 ℃; for 2h; Microwave irradiation;