3,4,4',5-tetramethoxy-2'-(dimethylaminocarbonyloxythio)-benzophenone

Base Information

• Chemical Name: 3,4,4',5-tetramethoxy-2'-(dimethylaminocarbonyloxythio)-benzophenone
• CAS No.: 154094-10-7
• Molecular Formula: C₂₀H₂₃NO₆S
• Molecular Weight: 405.472
• Mol file: 154094-10-7.mol

Synonyms:3,4,4',5-tetramethoxy-2'-(dimethylaminocarbonyloxythio)-benzophenone

Chemical Property of 3,4,4',5-tetramethoxy-2'-(dimethylaminocarbonyloxythio)-benzophenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4,4',5-tetramethoxy-2'-(dimethylaminocarbonyloxythio)-benzophenone

There total 3 articles about 3,4,4',5-tetramethoxy-2'-(dimethylaminocarbonyloxythio)-benzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Dimethyl-thiocarbamic acid O-[5-methoxy-2-(3,4,5-trimethoxy-benzoyl)-phenyl] ester → 3,4,4',5-tetramethoxy-2'-(dimethylaminocarbonyloxythio)-benzophenone (154094-10-7)

Guidance literature:

In diphenylether; at 250 - 260 ℃; for 24h; Yield given;

DOI:10.1016/S0040-4020(01)88028-5

Reference yield:

2,3',4,4',5'-Pentamethoxybenzophenon (55744-84-8) → 3,4,4',5-tetramethoxy-2'-(dimethylaminocarbonyloxythio)-benzophenone (154094-10-7)

Guidance literature:

Multi-step reaction with 3 steps

1: BBr₃ / CH₂Cl₂ / 0.75 h / Ambient temperature

2: KOt-Bu, 18-crown-6 / tetrahydrofuran / 1.) reflux, 5 h; 2.) RT, 20 h

3: diphenyl ether / 24 h / 250 - 260 °C

With 18-crown-6 ether; potassium tert-butylate; boron tribromide; In tetrahydrofuran; diphenylether; dichloromethane;

DOI:10.1016/S0040-4020(01)88028-5

Reference yield:

3,4,4',5'-tetramethoxy-2'-hydroxybenzophenone (62495-39-0) → 3,4,4',5-tetramethoxy-2'-(dimethylaminocarbonyloxythio)-benzophenone (154094-10-7)

Guidance literature:

Multi-step reaction with 2 steps

1: KOt-Bu, 18-crown-6 / tetrahydrofuran / 1.) reflux, 5 h; 2.) RT, 20 h

2: diphenyl ether / 24 h / 250 - 260 °C

With 18-crown-6 ether; potassium tert-butylate; In tetrahydrofuran; diphenylether;

DOI:10.1016/S0040-4020(01)88028-5

upstream raw materials:

3,4,4',5'-tetramethoxy-2'-hydroxybenzophenone

2,3',4,4',5'-Pentamethoxybenzophenon

Downstream raw materials:

3,4,4',5-tetramethoxy-2'-mercaptobenzophenone