5-amino-2-phenyl-7-trichloromethyl-1,2,4-triazolo[1,5-a][1,3,5]triazine

Base Information

• Chemical Name: 5-amino-2-phenyl-7-trichloromethyl-1,2,4-triazolo[1,5-a][1,3,5]triazine
• CAS No.: 1095050-82-0
• Molecular Formula: C₁₁H₇Cl₃N₆
• Molecular Weight: 329.576
• Mol file: 1095050-82-0.mol

Synonyms:5-amino-2-phenyl-7-trichloromethyl-1,2,4-triazolo[1,5-a][1,3,5]triazine

Chemical Property of 5-amino-2-phenyl-7-trichloromethyl-1,2,4-triazolo[1,5-a][1,3,5]triazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-amino-2-phenyl-7-trichloromethyl-1,2,4-triazolo[1,5-a][1,3,5]triazine

There total 2 articles about 5-amino-2-phenyl-7-trichloromethyl-1,2,4-triazolo[1,5-a][1,3,5]triazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

N-(3-phenyl-1H-1,2,4-triazol-5-yl)guanidine (92876-89-6) + trichloroacetonitrile (545-06-2) → 5-amino-2-phenyl-7-trichloromethyl-1,2,4-triazolo[1,5-a][1,3,5]triazine (1095050-82-0)

Guidance literature:

In toluene; for 7h; Reflux;

DOI:10.1016/j.tetlet.2008.10.003

Reference yield:

benzoic acid hydrazide (613-94-5) → 5-amino-2-phenyl-7-trichloromethyl-1,2,4-triazolo[1,5-a][1,3,5]triazine (1095050-82-0)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogenchloride

2: Alkaline conditions

3: toluene / 7 h / Heating

With hydrogenchloride; In toluene;

DOI:10.1016/j.jfluchem.2015.03.010

Reference yield: 98.0%

5-amino-2-phenyl-7-trichloromethyl-1,2,4-triazolo[1,5-a][1,3,5]triazine (1095050-82-0) + ethylamine (75-04-7,85404-22-4) → C12H13N7 (1095050-88-6)

Guidance literature:

In water; at 0 - 20 ℃; Cooling with ice;

DOI:10.1016/j.tetlet.2008.10.003

upstream raw materials:

N-(3-phenyl-1H-1,2,4-triazol-5-yl)guanidine

trichloroacetonitrile

benzoic acid hydrazide

Downstream raw materials:

C₁₄H₁₅N₇

C₁₅H₁₇N₇

C₁₄H₁₅N₇O

C₁₅H₁₈N₈