Chemical Property of Trifluoroacetaldehyde hydrate
Chemical Property:
- Vapor Pressure:4740mmHg at 25°C
- Melting Point:69-70℃
- Refractive Index:1.33
- Boiling Point:141.1°Cat760mmHg
- PKA:10.22±0.41(Predicted)
- Flash Point:39.2°C
- PSA：40.46000
- Density:1.582g/cm3
- LogP:-0.14060
- Water Solubility.:Soluble in water.
- XLogP3:0
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:5
- Rotatable Bond Count:0
- Exact Mass:116.00851382
- Heavy Atom Count:7
- Complexity:56.4
- Purity/Quality:
-
99% *data from raw suppliers
FluoralHydrate *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:T
- Statements:
20/21/22-43-36-22-11
- Safety Statements:
24/25-36/37-26-16
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C(C(F)(F)F)(O)O
-
Uses
Trifluoroacetaldehyde monohydrate is used as an agricultural
chemical, a drug and therapeutic agent, a fungicide, bactericide,
and wood preservative. One general application of trifluoroacetaldehyde is the preparation of trifluoroethylamino derivatives via reductive amination reaction. This synthesis includes the formation of the corresponding N,O-acetal intermediates followed by their reduction using NaBH4?or 2-picoline borane complex, affording the target trifluoroethylamino compounds in moderate to good yields. Another general application of trifluoroacetaldehyde is the synthesis of chiral α-substituted trifluoroethylamino compounds.
