(-)-(3'R,4'R,5'S)-3-[(2',3'-diphenyl-5'-methylisoxazolidin-4'-yl)carbonyl]-1,3-thiazolidin-2-thione

Base Information

• Chemical Name: (-)-(3'R,4'R,5'S)-3-[(2',3'-diphenyl-5'-methylisoxazolidin-4'-yl)carbonyl]-1,3-thiazolidin-2-thione
• CAS No.: 851078-02-9
• Molecular Formula: C₂₀H₂₀N₂O₂S₂
• Molecular Weight: 384.523

Synonyms:(-)-(3'R,4'R,5'S)-3-[(2',3'-diphenyl-5'-methylisoxazolidin-4'-yl)carbonyl]-1,3-thiazolidin-2-thione

Chemical Property of (-)-(3'R,4'R,5'S)-3-[(2',3'-diphenyl-5'-methylisoxazolidin-4'-yl)carbonyl]-1,3-thiazolidin-2-thione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (-)-(3'R,4'R,5'S)-3-[(2',3'-diphenyl-5'-methylisoxazolidin-4'-yl)carbonyl]-1,3-thiazolidin-2-thione

There total 1 articles about (-)-(3'R,4'R,5'S)-3-[(2',3'-diphenyl-5'-methylisoxazolidin-4'-yl)carbonyl]-1,3-thiazolidin-2-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C,N-diphenylnitrone (201024-81-9) + (E)-1-(2-thioxothiazolidin-3-yl)but-2-en-1-one → (-)-(3'R,4'R,5'S)-3-[(2',3'-diphenyl-5'-methylisoxazolidin-4'-yl)carbonyl]-1,3-thiazolidin-2-thione (851078-02-9) + (+)-(3'S,4'S,5'R)-3-[(2',3'-diphenyl-5'-methylisoxazolidin-4'-yl)carbonyl]-1,3-thiazolidin-2-thione

Guidance literature:

With (R)-BINIM-DCOH; nickel(II) perchlorate; In chloroform; at 20 ℃; for 15h; Title compound not separated from byproducts;

DOI:10.1021/ol050397h

Reference yield: 69.0%

(-)-(3'R,4'R,5'S)-3-[(2',3'-diphenyl-5'-methylisoxazolidin-4'-yl)carbonyl]-1,3-thiazolidin-2-thione (851078-02-9) + dimethylenecyclourethane (497-25-6) → exo-(3R,4S,5S)-3-<(5-methyl-2,3-diphenyl-1,3-isoxazolidin-4'-yl)carbonyl>-1,3-oxazolidin-2-one

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; at 0 - 20 ℃; for 3.25h;

DOI:10.1021/ol050397h

Reference yield: 53.0%

(-)-(3'R,4'R,5'S)-3-[(2',3'-diphenyl-5'-methylisoxazolidin-4'-yl)carbonyl]-1,3-thiazolidin-2-thione (851078-02-9) → (3,4-cis;4,5-trans) 4-hydroxymethyl-5-methyl-2,3-diphenyl-isoxazolidine

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; water; at 20 ℃; for 1.5h;

DOI:10.1021/ol050397h

upstream raw materials:

C,N-diphenylnitrone

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 851078-02-9 (-)-(3'R,4'R,5'S)-3-[(2',3'-diphenyl-5'-methylisoxazolidin-4'-yl)carbonyl]-1,3-thiazolidin-2-thione

Send

Send

Metric Ton KG G Pound L ML

Send

Send