2-Fluoro-4-methoxybenzamide

Base Information

Chemical Name:2-Fluoro-4-methoxybenzamide
CAS No.:874804-31-6
Molecular Formula:C₈H₈FNO₂
Molecular Weight:169.155
Hs Code.:2924297099
DSSTox Substance ID:DTXSID601310503
Mol file:874804-31-6.mol

Synonyms:2-FLUORO-4-METHOXYBENZAMIDE;874804-31-6;MFCD01117440;SCHEMBL72082;DTXSID601310503;AKOS006242762;SY228290;TS-02292;CS-0456638;G10334;Z87614977

Suppliers and Price of 2-Fluoro-4-methoxybenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Fluoro-4-methoxybenzamide
50mg
$ 45.00

SynQuest Laboratories
2-Fluoro-4-methoxybenzamide
10 g
$ 311.00

SynQuest Laboratories
2-Fluoro-4-methoxybenzamide
5 g
$ 175.00

Matrix Scientific
2-Fluoro-4-methoxybenzamide 97%
1g
$ 157.00

Crysdot
2-Fluoro-4-methoxybenzamide 95+%
10g
$ 424.00

Chemcia Scientific
2-Fluoro-4-methoxy-benzamide ＞95%
5 G
$ 250.00

Chemcia Scientific
2-Fluoro-4-methoxy-benzamide ＞95%
2 G
$ 120.00

Atlantic Research Chemicals
2-Fluoro-4-methoxybenzamide 95%
1gm:
$ 69.98

Alichem
2-Fluoro-4-methoxybenzamide
1g
$ 1490.00

Alichem
2-Fluoro-4-methoxybenzamide
500mg
$ 855.75

Total 5 raw suppliers

Chemical Property of 2-Fluoro-4-methoxybenzamide

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:169.05390666
Heavy Atom Count:12
Complexity:174

Purity/Quality:

98% ^*data from raw suppliers

2-Fluoro-4-methoxybenzamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC(=C(C=C1)C(=O)N)F

Technology Process of 2-Fluoro-4-methoxybenzamide

There total 3 articles about 2-Fluoro-4-methoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 2.0%

: 124-41-4
sodium methylate

: 1583-58-0
2,4-difluoro-benzoic acid

: 874804-07-6
4-fluoro-2-methoxy-benzamide

: 874804-31-6
2-fluoro-4-methoxy-benzamide

Guidance literature:: sodium methylate; 2,4-difluoro-benzoic acid; In dimethyl sulfoxide; at 80 ℃; for 25h;

With thionyl chloride; N,N-dimethyl-formamide; for 4h; Reflux;

With ammonium hydroxide; In dichloromethane; water; at 20 ℃; Cooling;

Reference yield:

: 321-24-4
2-Fluor-4-methoxybenzoesaurechlorid

: 874804-31-6
2-fluoro-4-methoxy-benzamide

Guidance literature:: With ammonium hydroxide; In ethyl acetate; at 0 ℃; for 0.5h;
DOI:10.1016/j.ejmech.2014.07.108

Reference yield:

: 394-42-3
2-fluoro-4-methoxy-benzoic acid

: 874804-31-6
2-fluoro-4-methoxy-benzamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: N,N-dimethyl-formamide / dichloromethane / 5 h / 0 - 40 °C / Inert atmosphere

1.2: Inert atmosphere

2.1: ammonium hydroxide / ethyl acetate / 0.5 h / 0 °C

With ammonium hydroxide; N,N-dimethyl-formamide; In dichloromethane; ethyl acetate;
DOI:10.1016/j.ejmech.2014.07.108