1,1-dimethylethyl ({3-[(4-acetyl-3-{[(5-chloro-2-thienyl)sulfonyl]amino}-1H-indazol-1-yl)methyl]phenyl}methyl)carbamate

Base Information

Chemical Name:1,1-dimethylethyl ({3-[(4-acetyl-3-{[(5-chloro-2-thienyl)sulfonyl]amino}-1H-indazol-1-yl)methyl]phenyl}methyl)carbamate
CAS No.:1240518-67-5
Molecular Formula:C₂₆H₂₇ClN₄O₅S₂
Molecular Weight:575.109
Hs Code.:

Synonyms:1,1-dimethylethyl ({3-[(4-acetyl-3-{[(5-chloro-2-thienyl)sulfonyl]amino}-1H-indazol-1-yl)methyl]phenyl}methyl)carbamate

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Chemical Property of 1,1-dimethylethyl ({3-[(4-acetyl-3-{[(5-chloro-2-thienyl)sulfonyl]amino}-1H-indazol-1-yl)methyl]phenyl}methyl)carbamate

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Technology Process of 1,1-dimethylethyl ({3-[(4-acetyl-3-{[(5-chloro-2-thienyl)sulfonyl]amino}-1H-indazol-1-yl)methyl]phenyl}methyl)carbamate

There total 1 articles about 1,1-dimethylethyl ({3-[(4-acetyl-3-{[(5-chloro-2-thienyl)sulfonyl]amino}-1H-indazol-1-yl)methyl]phenyl}methyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1240518-64-2
1,1-dimethylethyl ({3-[(3-{[(5-chloro-2-thienyl)sulfonyl]amino}-4-cyano-1H-indazol-1-yl)methyl]phenyl}methyl)carbamate

: 75-16-1
methylmagnesium bromide

: 1240518-67-5
1,1-dimethylethyl ({3-[(4-acetyl-3-{[(5-chloro-2-thienyl)sulfonyl]amino}-1H-indazol-1-yl)methyl]phenyl}methyl)carbamate

Guidance literature:: 1,1-dimethylethyl ({3-[(3-{[(5-chloro-2-thienyl)sulfonyl]amino}-4-cyano-1H-indazol-1-yl)methyl]phenyl}methyl)carbamate; methylmagnesium bromide; In tetrahydrofuran; diethyl ether; at 0 - 20 ℃;

With hydrogenchloride; water; In tetrahydrofuran; diethyl ether; at 0 ℃;

Reference yield: 76.0%

: 1240518-67-5
1,1-dimethylethyl ({3-[(4-acetyl-3-{[(5-chloro-2-thienyl)sulfonyl]amino}-1H-indazol-1-yl)methyl]phenyl}methyl)carbamate

: 75-16-1
methylmagnesium bromide

: 1240518-69-7
N-[1-{[3-(aminomethyl)phenyl]methyl}-4-(1-hydroxy-1-methylethyl)-1H-indazol-3-yl]-5-chloro-2-thiophenesulfonamide

Guidance literature:: 1,1-dimethylethyl ({3-[(4-acetyl-3-{[(5-chloro-2-thienyl)sulfonyl]amino}-1H-indazol-1-yl)methyl]phenyl}methyl)carbamate; methylmagnesium bromide; In tetrahydrofuran; diethyl ether; at 20 ℃;

With hydrogenchloride; In tetrahydrofuran; diethyl ether; water;