benzyl 4,4-diphenyl-2-((N-(phenylsulfonyl)phenylsulfonamido)methyl)pyrrolidine-1-carboxylate

Base Information

• Chemical Name: benzyl 4,4-diphenyl-2-((N-(phenylsulfonyl)phenylsulfonamido)methyl)pyrrolidine-1-carboxylate
• CAS No.: 1124311-71-2
• Molecular Formula: C₃₇H₃₄N₂O₆S₂
• Molecular Weight: 666.819
• Mol file: 1124311-71-2.mol

Synonyms:benzyl 4,4-diphenyl-2-((N-(phenylsulfonyl)phenylsulfonamido)methyl)pyrrolidine-1-carboxylate

Chemical Property of benzyl 4,4-diphenyl-2-((N-(phenylsulfonyl)phenylsulfonamido)methyl)pyrrolidine-1-carboxylate

Chemical Property:

Purity/Quality:

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Technology Process of benzyl 4,4-diphenyl-2-((N-(phenylsulfonyl)phenylsulfonamido)methyl)pyrrolidine-1-carboxylate

There total 1 articles about benzyl 4,4-diphenyl-2-((N-(phenylsulfonyl)phenylsulfonamido)methyl)pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

benzyl (5-methyl-2,2-diphenylhex-4-en-1-yl)carbamate (887131-39-7) + N-fluorobis(benzenesulfon)imide (133745-75-2) → benzyl 4,4-diphenyl-2-((N-(phenylsulfonyl)phenylsulfonamido)methyl)pyrrolidine-1-carboxylate (1124311-71-2)

Guidance literature:

With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; palladium(II) trifluoroacetate; triethylammonium benzenesulfonimide; In ethyl acetate; at 20 ℃; for 18h; Inert atmosphere;

DOI:10.1021/ol9000087

Reference yield: 87.0%

benzyl 4,4-diphenyl-2-((N-(phenylsulfonyl)phenylsulfonamido)methyl)pyrrolidine-1-carboxylate (1124311-71-2) → benzyl 4,4-diphenyl-2-(phenylsulfonamidomethyl)pyrrolidine-1-carboxylate (1124311-97-2)

Guidance literature:

benzyl 4,4-diphenyl-2-((N-(phenylsulfonyl)phenylsulfonamido)methyl)pyrrolidine-1-carboxylate; With potassium hydroxide; In ethanol; for 18h; Reflux; Inert atmosphere;

With hydrogenchloride; water; In ethanol; Inert atmosphere;

DOI:10.1021/ol9000087

Reference yield: 79.0%

benzyl 4,4-diphenyl-2-((N-(phenylsulfonyl)phenylsulfonamido)methyl)pyrrolidine-1-carboxylate (1124311-71-2) → N-((4,4-diphenylpyrrolidin-2-yl)methyl)-N-(phenylsulfonyl)benzenesulfonamide (1124312-00-0)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In ethyl acetate; for 36h; under 98260.7 Torr;

DOI:10.1021/ol9000087

upstream raw materials:

benzyl (5-methyl-2,2-diphenylhex-4-en-1-yl)carbamate

N-fluorobis(benzenesulfon)imide

Downstream raw materials:

benzyl 4,4-diphenyl-2-(phenylsulfonamidomethyl)pyrrolidine-1-carboxylate

N-((4,4-diphenylpyrrolidin-2-yl)methyl)-N-(phenylsulfonyl)benzenesulfonamide