P-Methoxystilbene

Base Information

• Chemical Name: P-Methoxystilbene
• CAS No.: 1694-19-5
• Molecular Formula: C15H14 O
• Molecular Weight: 210.276
• Hs Code.: 2909309090
• European Community (EC) Number: 214-530-7,622-359-8
• NSC Number: 149956,2139
• UNII: 5EL148B7HG
• Nikkaji Number: J101.823J,J303.851C
• Wikidata: Q27116413
• Metabolomics Workbench ID: 27962
• ChEMBL ID: CHEMBL2387063
• Mol file: 1694-19-5.mol

Synonyms:4-Methoxystilbene;1142-15-0;P-METHOXYSTILBENE;1694-19-5;4-Methoxy-trans-stilbene;trans-4-Methoxystilbene;1-Methoxy-4-((E)-styryl)-benzene;Anisole, p-styryl-;(E)-4-Methoxystilbene;1-(p-Methoxyphenyl)-2-phenylethene;Benzene, 1-methoxy-4-(2-phenylethenyl)-;1-Methoxy-4-[(E)-2-phenylethenyl]benzene;1-Methoxy-4-(2-phenylethenyl)benzene;1-Methoxy-4-styrylbenzene;1-Methoxy-4-(2-phenylethenyl)-benzene;CHEBI:35094;UNII-5EL148B7HG;5EL148B7HG;CHEMBL2387063;NSC-2139;EINECS 214-530-7;Benzene,1-methoxy-4-(2-phenylethenyl)-;p-Methoxystilben;Anisole,p-styryl-;MFCD00017178;trans-p-Methoxystilbene;4-Methoxy-trans-stilben;METHOXYSTILBENE ,4-;Anisole, p-styryl-, (E)-;SCHEMBL699620;SCHEMBL699621;STILBENE, 4-METHOXY-;(e)-1-methoxy-4-styrylbenzene;XWYXLYCDZKRCAD-BQYQJAHWSA-;NSC2139;BAA69419;NSC 2139;1-(4-methoxyphenyl)-2-phenylethene;BDBM50140154;LMPK13090021;NSC149956;STK751066;AKOS001720565;NSC-149956;PS-8014;NCGC00332015-01;AC-20796;AS-64321;1-methoxy-4-[(1E)-2-phenylethenyl]benzene;CS-0206534;M2964;1-(P-METHOXY)PHENYL-2-PHENYLETHYLENE;1-methoxy-4-[(E)-2-phenyl-1-ethenyl]benzene;1-Phenyl-2-(4-methoxy-phenyl)-A currencythylen;AB01325670-02;A803152;Benzene, 1-methoxy-4-(2-phenylethenyl)-, (E)-;2-(4-Nitrophenyl)oxazole-4-carboxylicacidethylester;J-003061;Q27116413

Chemical Property of P-Methoxystilbene

Chemical Property:

• Melting Point: 134.0 to 138.0 °C
• Refractive Index: 1.5725 (estimate)
• Boiling Point: 341.5°Cat760mmHg
• Flash Point: 135.4°C
• PSA: 9.23000
• Density: 1.069g/cm³
• LogP: 3.86560
• XLogP3: 4.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 210.104465066
• Heavy Atom Count: 16
• Complexity: 208

Purity/Quality:

97% ^*data from raw suppliers

trans-4-Methoxystilbene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C=CC2=CC=CC=C2
• Isomeric SMILES: COC1=CC=C(C=C1)/C=C/C2=CC=CC=C2

Technology Process of P-Methoxystilbene

There total 539 articles about P-Methoxystilbene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

1-bromo-4-methoxy-benzene (104-92-7) + trans-2-phenylvinylboronic acid (6783-05-7) → styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + E-1-(phenyl)-2-(4'-methoxyphenyl)ethene (1694-19-5)

Guidance literature:

With potassium carbonate; In water; at 100 ℃; for 5h;

DOI:10.1016/j.jorganchem.2009.01.016

Reference yield: 71.0%

Benzyl phenyl sulfone (3112-88-7) + 4-Methoxybenzyl alcohol (105-13-5) → E-1-(phenyl)-2-(4'-methoxyphenyl)ethene (1694-19-5) + potassium benzenesulfonate (934-55-4)

Guidance literature:

With C₂₄H₂₀ClN₂OPRu; potassium tert-butylate; In 1,4-dioxane; at 125 ℃; for 5h; Inert atmosphere; Schlenk technique; Glovebox;

DOI:10.1002/anie.201407281

Reference yield: 39.0%

4-(phenylethynyl)anisole (7380-78-1) → trans-4-Hydroxystilbene (6554-98-9) + E-1-(phenyl)-2-(4'-methoxyphenyl)ethene (1694-19-5)

Guidance literature:

With selenium; water; potassium acetate; In N,N-dimethyl-formamide; at 150 ℃; for 24h; stereoselective reaction; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.orglett.8b02244

upstream raw materials:

piperonal

4-methoxy-benzaldehyde

benzylmagnesium chloride

styrene

Downstream raw materials:

cis-4-methoxystilbene

(α,α'-dibromo-bibenzyl-4-yl)-methyl ether

1-(4-methoxyphenyl)-2-phenyl-ethane-1,2-diol

1-(4-methoxyphenyl)-2-phenylethane