6-chloro-1,4-dioxaspiro[4.5]decane

Base Information

• Chemical Name: 6-chloro-1,4-dioxaspiro[4.5]decane
• CAS No.: 6954-16-1
• Molecular Formula: C8H13 Cl O2
• Molecular Weight: 176.643
• Mol file: 6954-16-1.mol

Synonyms:2-Chlorocyclohexanonecyclic ethylene ketal; 2-Chlorocyclohexanone ethylene ketal;6-Chloro-1,4-dioxaspiro[4.5]decane; NSC 69177

Chemical Property of 6-chloro-1,4-dioxaspiro[4.5]decane

Chemical Property:

• Vapor Pressure: 0.0115mmHg at 25°C
• Boiling Point: 270.2°Cat760mmHg
• Flash Point: 115.4°C
• Density: 1.18g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-chloro-1,4-dioxaspiro[4.5]decane

There total 2 articles about 6-chloro-1,4-dioxaspiro[4.5]decane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + ethylene glycol (107-21-1) → (R,S)-6-chloro-1,4-dioxaspiro<4.5>decane (6954-16-1)

Guidance literature:

With N-chloro-succinimide; at 20 ℃; for 24h;

DOI:10.1016/j.tet.2016.05.064

Reference yield:

ethylene glycol (107-21-1) + 2-Chlorocyclohexanone (822-87-7) → (R,S)-6-chloro-1,4-dioxaspiro<4.5>decane (6954-16-1)

Guidance literature:

With toluene-4-sulfonic acid; benzene;

Reference yield:

(R,S)-6-chloro-1,4-dioxaspiro<4.5>decane (6954-16-1) → cyclohexenone (930-68-7)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium hydroxide; ammonium chloride; diethylene glycol

2: HCl; water

With hydrogenchloride; potassium hydroxide; ammonium chloride; water; diethylene glycol;

upstream raw materials:

ethylene glycol

2-Chlorocyclohexanone

cyclohexanone

Downstream raw materials:

1,4-dioxa-spiro[4.5]dec-6-ene

cyclohexenone