(2R,2'S)-2,2'-oxydipropionic acid

Base Information

• Chemical Name: (2R,2'S)-2,2'-oxydipropionic acid
• CAS No.: 18609-85-3
• Molecular Formula: C₆H₁₀O₅
• Molecular Weight: 162.142
• Mol file: 18609-85-3.mol

Synonyms:(2R,2'S)-2,2'-oxydipropionic acid

Chemical Property of (2R,2'S)-2,2'-oxydipropionic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,2'S)-2,2'-oxydipropionic acid

There total 14 articles about (2R,2'S)-2,2'-oxydipropionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

S,S-dilactic acid diethyl ester (125948-52-9) → (2S,2'S)-2,2'-oxydipropionic acid (14711-85-4,18609-85-3,19201-34-4)

Guidance literature:

S,S-dilactic acid diethyl ester; With sodium hydroxide; In methanol; at 20 ℃; Inert atmosphere;

With sulfuric acid; In diethyl ether; Inert atmosphere; Cooling with ice;

DOI:10.1002/chem.201806161

Reference yield:

ethyl 2-hydroxyacetate sodium salt (38233-96-4) → 1,1'-bis(1,1'-carboxyethyl) ether (19201-34-4) + (2R,2'S)-2,2'-oxydipropionic acid (18609-85-3)

Guidance literature:

nachfolgende Verseifung; Trennung der beiden Isomeren erfolgt durch fraktionierte Krystallisation des Magnesiumsalzes;

Reference yield:

1,1'-bis(1,1'-carboxyethyl) ether (19201-34-4) → DL-dilactylic acid (14711-85-4,18609-85-3,19201-34-4)

Guidance literature:

Multi-step reaction with 3 steps

1: concentrated H₂SO₄

2: water; NH₃ / Trennung der Isomeren erfolgt durch fraktionierte Krystallisation aus Aethanol

3: H₂SO₄

With sulfuric acid; ammonia; water;

upstream raw materials:

ethyl 2-hydroxyacetate sodium salt

tetrachloromethane

L-dilactylic acid diamide

S,S-dilactic acid diethyl ester

Downstream raw materials:

1,1'-bis(1,1'-carboxyethyl) ether

carbon dioxide

water

acetaldehyde