Acetic acid (S)-2-(4-benzyloxy-2-nitro-phenyl)-3-methanesulfonyloxy-propyl ester

Base Information

Chemical Name:Acetic acid (S)-2-(4-benzyloxy-2-nitro-phenyl)-3-methanesulfonyloxy-propyl ester
CAS No.:186144-33-2
Molecular Formula:C₁₉H₂₁NO₈S
Molecular Weight:423.444
Hs Code.:

Synonyms:Acetic acid (S)-2-(4-benzyloxy-2-nitro-phenyl)-3-methanesulfonyloxy-propyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Acetic acid (S)-2-(4-benzyloxy-2-nitro-phenyl)-3-methanesulfonyloxy-propyl ester

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Technology Process of Acetic acid (S)-2-(4-benzyloxy-2-nitro-phenyl)-3-methanesulfonyloxy-propyl ester

There total 2 articles about Acetic acid (S)-2-(4-benzyloxy-2-nitro-phenyl)-3-methanesulfonyloxy-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 124-63-0
methanesulfonyl chloride

: 184046-61-5
(2R)-3-acetoxy-2-[4-(benzyloxy)-2-nitrophenyl]propane-1-ol

: 186144-33-2
Acetic acid (S)-2-(4-benzyloxy-2-nitro-phenyl)-3-methanesulfonyloxy-propyl ester

Guidance literature:: With triethylamine; In dichloromethane;
DOI:10.1246/cl.1997.11

Reference yield:

: 106014-83-9
2-[4-(benzyloxy)-2-nitrophenyl]propane-1,3-diol

: 186144-33-2
Acetic acid (S)-2-(4-benzyloxy-2-nitro-phenyl)-3-methanesulfonyloxy-propyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: porcine pancreatic lipase on Celit, powdered molecular sieves / 3 h

2: 99 percent / triethylamine / CH₂Cl₂

With molecular sieve; porcine pancreatic lipase on Celit; triethylamine; In dichloromethane;
DOI:10.1246/cl.1997.11