2-(trimethylsilyl)ethyl (S,E)-3,3,3-trifluoro-2-(1-phenylethylimino)propanoate

Base Information

• Chemical Name: 2-(trimethylsilyl)ethyl (S,E)-3,3,3-trifluoro-2-(1-phenylethylimino)propanoate
• CAS No.: 1039136-55-4
• Molecular Formula: C₁₆H₂₂F₃NO₂Si
• Molecular Weight: 345.437
• Mol file: 1039136-55-4.mol

Synonyms:2-(trimethylsilyl)ethyl (S,E)-3,3,3-trifluoro-2-(1-phenylethylimino)propanoate

Chemical Property of 2-(trimethylsilyl)ethyl (S,E)-3,3,3-trifluoro-2-(1-phenylethylimino)propanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(trimethylsilyl)ethyl (S,E)-3,3,3-trifluoro-2-(1-phenylethylimino)propanoate

There total 1 articles about 2-(trimethylsilyl)ethyl (S,E)-3,3,3-trifluoro-2-(1-phenylethylimino)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(Trimethylsilyl)ethanol (2916-68-9) + carbon monoxide (201230-82-2) + 2,2,2-trifluoro-N-(1-phenyl-ethyl)-acetimidoyl iodide → 2-(trimethylsilyl)ethyl (S,E)-3,3,3-trifluoro-2-(1-phenylethylimino)propanoate (1039136-55-4)

Guidance literature:

With potassium carbonate; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In N,N-dimethyl-formamide; toluene; under 760.051 Torr;

DOI:10.1021/jo800567a

Reference yield: 79.0%

2-(trimethylsilyl)ethyl (S,E)-3,3,3-trifluoro-2-(1-phenylethylimino)propanoate (1039136-55-4) + benzyl bromide (100-39-0) → benzyl (S,E)-3,3,3-trifluoro-2-(1-phenylethylimino)propanoate (1039136-72-5)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1021/jo800567a

upstream raw materials:

2-(Trimethylsilyl)ethanol

carbon monoxide

Downstream raw materials:

benzyl (S,E)-3,3,3-trifluoro-2-(1-phenylethylimino)propanoate