Technology Process of benzyl 2-acetamido-5-amino-2,5-dideoxy-β-D-ribofuranoside monoacetate
There total 8 articles about benzyl 2-acetamido-5-amino-2,5-dideoxy-β-D-ribofuranoside monoacetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 85 percent / pyridine / 3 h / 0 °C
2: 1.) hydrogen / 1.) 10percent Pd-C / 1.) 1,4-dioxane/methanol, room temperature, 2.5 h; 2.)methanol, room temperature, 30 min
3: 1.) sodium azide / 1.) N,N-dimethylformamide, 90 degC; 2.) N,N-dimethylformamide, 90 degC
4: 68 percent / hydrochlorid acid, Amberlite IRA-45 resin / acetic acid / 4 h / 50 °C
5: 74 percent / hydrogen / 10percent pd-C / ethanol / 0.33 h / 40 °C
With
pyridine; hydrogenchloride; sodium azide; Amberlite IRA-45 resin; hydrogen;
palladium on activated charcoal;
In
ethanol; acetic acid;
DOI:10.1016/S0008-6215(00)85674-8
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 82 percent / pyridine / 3 h / 0 °C
2: 1.) sodium azide / 1.) N,N-dimethylformamide, 50 degC; 2.) N,N-dimethylformamide, 50 degC
3: 68 percent / hydrochlorid acid, Amberlite IRA-45 resin / acetic acid / 4 h / 50 °C
4: 74 percent / hydrogen / 10percent pd-C / ethanol / 0.33 h / 40 °C
With
pyridine; hydrogenchloride; sodium azide; Amberlite IRA-45 resin; hydrogen;
palladium on activated charcoal;
In
ethanol; acetic acid;
DOI:10.1016/S0008-6215(00)85674-8
