C₄₃H₄₆N₈O₄

Base Information

• Chemical Name: C₄₃H₄₆N₈O₄
• CAS No.: 1417529-78-2
• Molecular Formula: C₄₃H₄₆N₈O₄
• Molecular Weight: 738.889
• Mol file: 1417529-78-2.mol

Synonyms:C₄₃H₄₆N₈O₄

Chemical Property of C₄₃H₄₆N₈O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₃H₄₆N₈O₄

There total 4 articles about C₄₃H₄₆N₈O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

C36H39N7O5 (1417530-32-5) + benzylamine (100-46-9) → C43H46N8O4 (1417529-78-2)

Guidance literature:

With 2,6-dimethylpyridine; 2-(5-norbornene-2,3-dicarboximido)-1,1,3,3-tetramethyluronium tetrafluoroborates; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 23 ℃; for 0.5h; Reagent/catalyst;

DOI:10.1002/chem.201201337

Reference yield:

4-methyltrityl chloride (23429-44-9) → C43H46N8O4 (1417529-78-2)

Guidance literature:

Multi-step reaction with 5 steps

1: pyridine / dichloromethane / 4 h

2: triethylamine / dichloromethane / 3 h

3: N-ethyl-N,N-diisopropylamine; 2,6-dimethylpyridine; HATU / N,N-dimethyl-formamide / 12 h

4: lithium hydroxide / 1,4-dioxane; water / 2 h

5: N-ethyl-N,N-diisopropylamine; 2,6-dimethylpyridine; 2-(5-norbornene-2,3-dicarboximido)-1,1,3,3-tetramethyluronium tetrafluoroborates / N,N-dimethyl-formamide / 0.5 h / 23 °C

With pyridine; 2,6-dimethylpyridine; 2-(5-norbornene-2,3-dicarboximido)-1,1,3,3-tetramethyluronium tetrafluoroborates; triethylamine; N-ethyl-N,N-diisopropylamine; HATU; lithium hydroxide; In 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1002/chem.201201337

Reference yield:

C22H24N2 (1263044-93-4) → C43H46N8O4 (1417529-78-2)

Guidance literature:

Multi-step reaction with 4 steps

1: triethylamine / dichloromethane / 3 h

2: N-ethyl-N,N-diisopropylamine; 2,6-dimethylpyridine; HATU / N,N-dimethyl-formamide / 12 h

3: lithium hydroxide / 1,4-dioxane; water / 2 h

4: N-ethyl-N,N-diisopropylamine; 2,6-dimethylpyridine; 2-(5-norbornene-2,3-dicarboximido)-1,1,3,3-tetramethyluronium tetrafluoroborates / N,N-dimethyl-formamide / 0.5 h / 23 °C

With 2,6-dimethylpyridine; 2-(5-norbornene-2,3-dicarboximido)-1,1,3,3-tetramethyluronium tetrafluoroborates; triethylamine; N-ethyl-N,N-diisopropylamine; HATU; lithium hydroxide; In 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1002/chem.201201337

upstream raw materials:

C₃₆H₃₉N₇O₅

benzylamine

4-methyltrityl chloride

C₂₂H₂₄N₂

Downstream raw materials:

C₂₃H₃₀N₈O₄