23429-44-9

Basic information

• Product Name: 4-METHYLTRITYL CHLORIDE
• Synonyms: 4-METHYLTRIPHENYL CHLOROMETHANE;4-METHYLTRIPHENYLMETHYL CHLORIDE;4-METHYLTRITYL CHLORIDE;MTT-CL;RARECHEM AR PA 0033;4-Methyltrityl chlorid, 4-Methyltriphenylmethyl chloride;p-Tolyl-dibenzyl chloride;(Chloro(p-tolyl)Methylene)dibenzene
• CAS NO: 23429-44-9
• Molecular Formula: C₂₀H₁₇Cl
• Molecular Weight: 292.8
• Mol File: 23429-44-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 98-99℃
• Boiling Point: 405 °C at 760 mmHg
• Flash Point: 186.5 °C
• Appearance: /
• Density: 1.124
• Vapor Pressure: 2.12E-06mmHg at 25°C
• Refractive Index: 1.6
• Storage Temp.: -20°C
• CAS DataBase Reference: 4-METHYLTRITYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYLTRITYL CHLORIDE(23429-44-9)
• EPA Substance Registry System: 4-METHYLTRITYL CHLORIDE(23429-44-9)

Safety Data

• Hazardous Substances Data: 23429-44-9(Hazardous Substances Data)

Usage

General Description

4-Methyltrityl Chloride is a chemical compound that is primarily used in the field of organic chemistry. It is characterized as an aromatic compound with the chemical formula C21H19Cl. It is commonly used as a type of protecting group in the synthesis of peptides. 4-METHYLTRITYL CHLORIDE, known as an acylating agent, can prevent unwanted reactions, and is removed when no longer needed. It has a white crystalline appearance and is considered harmful if ingested or inhaled, due to its irritant properties. Its use must be handled with care, most especially if used in a closed-lab setting.

InChI:InChI=1/C20H17Cl/c1-16-12-14-19(15-13-16)20(21,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-15H,1H3

Upstream product

• 134-84-9 4-Methylbenzophenone 
• 119-61-9 benzophenone 
• 147246-89-7 diphenyl-p-tolyl-acetic acid 
• 108-86-1 bromobenzene 
• 108-88-3 toluene 
• 5440-76-6 (4-methylphenyl)diphenylmethanol 
• 106-38-7 para-bromotoluene 

Downstream Products

• 603-37-2 p-(diphenylmethyl)toluene 
• 1061736-89-7 (1S,2S,5S,6R)-3-aza-3-(fluoren-9-ylmethyloxycarbonyl)-6-{[(4-methylphenyl)diphenylmethyl]aminomethyl}bicyclo[3.1.0]hexane-2-carboxylic acid 
• 1061737-06-1 trans-4-{[(4-methylphenyl)diphenylmethyl]aminomethyl}-N-(fluoren-9-ylmethyloxycarbonyl)-L-proline 
• 1061737-21-0 trans-4-{[(4-methylphenyl)diphenylmethyl]amino}-N-(fluoren-9-ylmethyloxycarbonyl)-L-proline 
• 1061736-96-6 trans-3-{2-[(4-methylphenyl)diphenylmethyl]aminoethyl}-N-(9-fluorenylmethyl)-L-proline 
• 13947-74-5 p-Methylphenyl-diphenylmethyliumion 
• 470461-86-0 4-({[(4-Methylphenyl)diphenylmethyl]amino}methyl)-3-nitrobenzoic Acid 
• 118230-47-0 Ethyl(4-methyltrityl)ether 
• 127787-62-6 dimethyl <(4-methylphenyl)diphenylmethyl>phosphonate 
• 126979-56-4 <(4-methylphenyl)diphenylmethyl>cyclohexane 
• 120264-85-9 4-(Diphenyl-p-tolyl-methoxy)-benzonitrile 
• 21349-20-2 4-Methyl-trityl 
• 53060-12-1 diphenyl-p-tolylmethylamine 
• 137003-27-1 4-methyltriphenylacetonitrile oxide 

Relevant articles and documents

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The use of 4-methoxytrityl (monomethoxytrityl, Mmt) and 4-methyl-trityl (Mtt) groups of N1m-protection of Fmoc-His is described. Both groups being unaffected by base, e.g. piperidine and diethylamine, can be quantitatively removed under very mi

A Kinetic Study of the Rearrangement of Triarylacetonitrile Oxides

The thermal rearrangement of triphenylacetonitrile oxide (1a) to triphenylmethyl isocyanate (2) is a first-order process.Rate constants at five temperatures between 116 and 190 deg C were determined giving ΔH(excit.) = 9.3 +/- 1.1 kcal/mol and ΔS(excit.) = -58.2 +/- 2.4 cal/mol*K.The rearrangement of substituted triarylacetonitrile oxides (1b-d) occur only slightly faster than that of 1a.These results are interpreted in terms of a concerted single-step rearrangement in which the highly ordered transition state (6c) has a degree of radical character.