8-(2-chlorophenyl)-8-(6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl)-2,2-dimethyloctanoic acid hydrochloride

Base Information

Chemical Name:8-(2-chlorophenyl)-8-(6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl)-2,2-dimethyloctanoic acid hydrochloride
CAS No.:1373491-54-3
Molecular Formula:C₂₃H₃₀ClNO₃*ClH
Molecular Weight:440.41
Hs Code.:

Synonyms:8-(2-chlorophenyl)-8-(6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl)-2,2-dimethyloctanoic acid hydrochloride

Suppliers and Price of 8-(2-chlorophenyl)-8-(6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl)-2,2-dimethyloctanoic acid hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 8-(2-chlorophenyl)-8-(6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl)-2,2-dimethyloctanoic acid hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 8-(2-chlorophenyl)-8-(6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl)-2,2-dimethyloctanoic acid hydrochloride

There total 10 articles about 8-(2-chlorophenyl)-8-(6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl)-2,2-dimethyloctanoic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.3%

: 1373491-81-6
8-(2-chlorophenyl)-8-(6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl)-2,2-dimethyloctanoic acid ethyl ester

: 1373491-54-3
8-(2-chlorophenyl)-8-(6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl)-2,2-dimethyloctanoic acid hydrochloride

Guidance literature:: 8-(2-chlorophenyl)-8-(6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl)-2,2-dimethyloctanoic acid ethyl ester; With water; sodium hydroxide; In ethanol; for 6.5h; Reflux;

With hydrogenchloride; In water; pH=6;

Reference yield:

: 1121-46-6
2-Furan-2-yl-ethylamine

: 1373491-54-3
8-(2-chlorophenyl)-8-(6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl)-2,2-dimethyloctanoic acid hydrochloride

Guidance literature:: Multi-step reaction with 6 steps

1.1: water / 0.5 h / 20 °C

2.1: hydrogenchloride / N,N-dimethyl-formamide / Saturated solution

2.2: pH 11

3.1: dichloromethane / 1.5 h / 20 °C

4.1: hydrogenchloride / methanol / 5.5 h / 20 °C

5.1: potassium carbonate / N,N-dimethyl-formamide / 72 h / 60 °C / Inert atmosphere

6.1: sodium hydroxide; water / ethanol / 6.5 h / Reflux

6.2: pH 6

With hydrogenchloride; water; potassium carbonate; sodium hydroxide; In methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide;

Reference yield:

: 150322-87-5
4,5,6,7-tetrahydrofuro[3,2.-c]pyridine

: 1373491-54-3
8-(2-chlorophenyl)-8-(6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl)-2,2-dimethyloctanoic acid hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1.1: dichloromethane / 1.5 h / 20 °C

2.1: hydrogenchloride / methanol / 5.5 h / 20 °C

3.1: potassium carbonate / N,N-dimethyl-formamide / 72 h / 60 °C / Inert atmosphere

4.1: sodium hydroxide; water / ethanol / 6.5 h / Reflux

4.2: pH 6

With hydrogenchloride; water; potassium carbonate; sodium hydroxide; In methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;