Tiadenol

Base Information

• Chemical Name: Tiadenol
• CAS No.: 6964-20-1
• Molecular Formula: C14H30O2S2
• Molecular Weight: 294.523
• Hs Code.: 2930909090
• European Community (EC) Number: 230-165-6
• NSC Number: 66316
• UNII: 22251270CX
• DSSTox Substance ID: DTXSID50219903
• Nikkaji Number: J803.263G
• Wikipedia: Tiadenol
• Wikidata: Q7800043
• NCI Thesaurus Code: C152597
• Metabolomics Workbench ID: 154166
• ChEMBL ID: CHEMBL1697775
• Mol file: 6964-20-1.mol

Synonyms:2,2'-(decamethylenedithio)-diethanol;bis(2- hydroxyethylthio)-1,10-decane;bis(hydroxy-2-ethylthio)-1,10-decane;BS 530;Fonlipol;LL 1558;thiadenol;tiadenol;tiadenolo

Chemical Property of Tiadenol

Chemical Property:

• Vapor Pressure: 2.56E-10mmHg at 25°C
• Melting Point: 69.5°
• Boiling Point: 458.1°Cat760mmHg
• PKA: 14.21±0.10(Predicted)
• Flash Point: 222.3°C
• PSA: 91.06000
• Density: 1.042g/cm³
• LogP: 3.55820
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 15
• Exact Mass: 294.16872254
• Heavy Atom Count: 18
• Complexity: 130

Purity/Quality:

98%min ^*data from raw suppliers

TIADENOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCCCCSCCO)CCCCSCCO
• Therapeutic Function: Antihyperlipidemic

Technology Process of Tiadenol

There total 3 articles about Tiadenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1,10-dibromodecane (4101-68-2) + 2-hydroxyethanethiol (60-24-2) → thiadenol (6964-20-1)

Guidance literature:

With sodium hydroxide; for 2h; Heating;

DOI:10.1080/00304940509354957

Reference yield: 96.0%

1,10-decadiene (1647-16-1) + 2-hydroxyethanethiol (60-24-2) → thiadenol (6964-20-1)

Guidance literature:

With tert-butyl peroxypivalate; In acetonitrile; at 75 ℃; for 2h;

Reference yield:

→ thiadenol (6964-20-1)

Guidance literature:

1,10-Dibromdecan, Mercaptoethanol;

upstream raw materials:

1,10-dibromodecane

2-hydroxyethanethiol

1,10-decadiene

Refernces

• 1、 Ameduri, Bruno,Berrada, Khalid,Boutevin, Bernard,Bowden, Roy D.. "SYNTHESIS OF TELECHELIC MONODISPERSED DIOLS. PART 3. TELOMERIZATION OF NONCONJUGATED DIENES WITH COMMERCIALLY AVAILABLE OR SYNTHESIZED MERCAPTO-ALCOHOLS". . p. 39 - 48. Retrieved 2007/10/02.