3-Cyano-2-dicyanomethylene-5,5-dimethyl-4-(4'-ethynyl phenyl)-2,5-dihydrofuran

Base Information

• Chemical Name: 3-Cyano-2-dicyanomethylene-5,5-dimethyl-4-(4'-ethynyl phenyl)-2,5-dihydrofuran
• CAS No.: 1207268-71-0
• Molecular Formula: C₁₈H₁₁N₃O
• Molecular Weight: 285.305
• Mol file: 1207268-71-0.mol

Synonyms:3-Cyano-2-dicyanomethylene-5,5-dimethyl-4-(4'-ethynyl phenyl)-2,5-dihydrofuran

Chemical Property of 3-Cyano-2-dicyanomethylene-5,5-dimethyl-4-(4'-ethynyl phenyl)-2,5-dihydrofuran

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Cyano-2-dicyanomethylene-5,5-dimethyl-4-(4'-ethynyl phenyl)-2,5-dihydrofuran

There total 1 articles about 3-Cyano-2-dicyanomethylene-5,5-dimethyl-4-(4'-ethynyl phenyl)-2,5-dihydrofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

3-cyano-2-dicyanomethylene-5,5-dimethyl-4-(4'-trimethylsilylethynylphenyl)-2,5-dihydrofuran (1207268-70-9) → 3-Cyano-2-dicyanomethylene-5,5-dimethyl-4-(4'-ethynyl phenyl)-2,5-dihydrofuran (1207268-71-0)

Guidance literature:

With potassium fluoride; In tetrahydrofuran; methanol; at 20 ℃; for 24h;

Reference yield: 82.0%

3-Cyano-2-dicyanomethylene-5,5-dimethyl-4-(4'-ethynyl phenyl)-2,5-dihydrofuran (1207268-71-0) + 4-Diethylaminophenylazid (24573-95-3) → 2-{3-cyano-4-(4-(1-(4-diethylamino-phenyl)-1H-[1,2,3]triazol-4-yl)phenyl)-5,5-dimethyl-5H-furan-2-ylidene}malononitrile (1207268-76-5)

Guidance literature:

copper(II) sulfate; sodium L-ascorbate; In ethanol; water; at 20 - 60 ℃;

Reference yield: 65.0%

3-Cyano-2-dicyanomethylene-5,5-dimethyl-4-(4'-ethynyl phenyl)-2,5-dihydrofuran (1207268-71-0) + Phenyl azide (622-37-7) → 2-{3-cyano-5,5-dimethyl-4-[4-(1-phenyl-1H-[1,2,3]triazol-4-yl)phenyl]-5H-furan-2-ylidene}malononitrile (1207268-74-3)

Guidance literature:

3-Cyano-2-dicyanomethylene-5,5-dimethyl-4-(4'-ethynyl phenyl)-2,5-dihydrofuran; Phenyl azide; In ethanol; at 50 ℃;

copper(II) sulfate; sodium L-ascorbate; In ethanol; water; at 50 ℃;

upstream raw materials:

3-cyano-2-dicyanomethylene-5,5-dimethyl-4-(4'-trimethylsilylethynylphenyl)-2,5-dihydrofuran

Downstream raw materials:

2-{3-cyano-5,5-dimethyl-4-[4-(1-phenyl-1H-[1,2,3]triazol-4-yl)phenyl]-5H-furan-2-ylidene}malononitrile

2-{3-cyano-5,5-dimethyl-4-[4-(1-octyl-1H-[1,2,3]triazol-4-yl)phenyl]-5H-furan-2-ylidene}malononitrile

2-{3-cyano-4-(4-(1-(4-diethylamino-phenyl)-1H-[1,2,3]triazol-4-yl)phenyl)-5,5-dimethyl-5H-furan-2-ylidene}malononitrile