(4R,6R,7S)-(4-(2-oxo-4-([1,2,4]triazol-1-yl)-pyrimidin-1(2H)-yl)-6-[(4-methoxyphenyl)(diphenyl)methoxymethyl]-5-oxaspiro[2.4]hept-7-yl) isobutyrate

Base Information

Chemical Name:(4R,6R,7S)-(4-(2-oxo-4-([1,2,4]triazol-1-yl)-pyrimidin-1(2H)-yl)-6-[(4-methoxyphenyl)(diphenyl)methoxymethyl]-5-oxaspiro[2.4]hept-7-yl) isobutyrate
CAS No.:1202488-04-7
Molecular Formula:C₃₇H₃₇N₅O₆
Molecular Weight:647.731
Hs Code.:

Synonyms:(4R,6R,7S)-(4-(2-oxo-4-([1,2,4]triazol-1-yl)-pyrimidin-1(2H)-yl)-6-[(4-methoxyphenyl)(diphenyl)methoxymethyl]-5-oxaspiro[2.4]hept-7-yl) isobutyrate

Suppliers and Price of (4R,6R,7S)-(4-(2-oxo-4-([1,2,4]triazol-1-yl)-pyrimidin-1(2H)-yl)-6-[(4-methoxyphenyl)(diphenyl)methoxymethyl]-5-oxaspiro[2.4]hept-7-yl) isobutyrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4R,6R,7S)-(4-(2-oxo-4-([1,2,4]triazol-1-yl)-pyrimidin-1(2H)-yl)-6-[(4-methoxyphenyl)(diphenyl)methoxymethyl]-5-oxaspiro[2.4]hept-7-yl) isobutyrate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4R,6R,7S)-(4-(2-oxo-4-([1,2,4]triazol-1-yl)-pyrimidin-1(2H)-yl)-6-[(4-methoxyphenyl)(diphenyl)methoxymethyl]-5-oxaspiro[2.4]hept-7-yl) isobutyrate

There total 6 articles about (4R,6R,7S)-(4-(2-oxo-4-([1,2,4]triazol-1-yl)-pyrimidin-1(2H)-yl)-6-[(4-methoxyphenyl)(diphenyl)methoxymethyl]-5-oxaspiro[2.4]hept-7-yl) isobutyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 288-88-0
1,2,4-Triazole

: 1202488-01-4
(4R,6R,7S)-(4-(2,4-dioxopyrimidin-1(2H)-yl)-6-[(4-methoxyphenyldiphenyl)methoxymethyl]-5-oxaspiro[2.4]-hept-7-yl) isobutyrate

: 1202488-04-7
(4R,6R,7S)-(4-(2-oxo-4-([1,2,4]triazol-1-yl)-pyrimidin-1(2H)-yl)-6-[(4-methoxyphenyl)(diphenyl)methoxymethyl]-5-oxaspiro[2.4]hept-7-yl) isobutyrate

Guidance literature:: With triethylamine; trichlorophosphate; In dichloromethane; at 20 ℃; for 4h;
DOI:10.1021/jm101050a

Reference yield:

: 1202487-81-7
1-((4R,6R,7S)-7-hydroxy-6-((4-methoxyphenyl)(diphenyl)methoxymethyl)-5-oxaspiro[2.4]hept-4-yl)-1H-pyrimidin-2,4(1H,3H)-dione

: 1202488-04-7
(4R,6R,7S)-(4-(2-oxo-4-([1,2,4]triazol-1-yl)-pyrimidin-1(2H)-yl)-6-[(4-methoxyphenyl)(diphenyl)methoxymethyl]-5-oxaspiro[2.4]hept-7-yl) isobutyrate

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 20 °C / Cooling with cold water

2: triethylamine; trichlorophosphate / dichloromethane / 20 - 25 °C

With pyridine; triethylamine; trichlorophosphate; In dichloromethane;

Reference yield:

: 140902-02-9
1-((4R,6R,7S)-7-hydroxy-6-hydroxymethyl-5-oxaspiro[2.4]hept-4-yl)-1H-pyrimidin-2,4(1H,3H)-dione

: 1202488-04-7
(4R,6R,7S)-(4-(2-oxo-4-([1,2,4]triazol-1-yl)-pyrimidin-1(2H)-yl)-6-[(4-methoxyphenyl)(diphenyl)methoxymethyl]-5-oxaspiro[2.4]hept-7-yl) isobutyrate

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / 20 °C / Cooling with ice

2: pyridine / 20 °C / Cooling with cold water

3: triethylamine; trichlorophosphate / dichloromethane / 20 - 25 °C

With pyridine; triethylamine; trichlorophosphate; In dichloromethane;