1-(2'-Brom-3'-hydroxy-4'-methoxy-benzyl)-2-methyl-6,7-methylendioxy-1,2,3,4-tetrahydroisochinolin

Base Information

Chemical Name:1-(2'-Brom-3'-hydroxy-4'-methoxy-benzyl)-2-methyl-6,7-methylendioxy-1,2,3,4-tetrahydroisochinolin
CAS No.:116861-72-4
Molecular Formula:C₁₉H₂₀BrNO₄
Molecular Weight:406.276
Hs Code.:

Synonyms:1-(2'-Brom-3'-hydroxy-4'-methoxy-benzyl)-2-methyl-6,7-methylendioxy-1,2,3,4-tetrahydroisochinolin

Suppliers and Price of 1-(2'-Brom-3'-hydroxy-4'-methoxy-benzyl)-2-methyl-6,7-methylendioxy-1,2,3,4-tetrahydroisochinolin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(2'-Brom-3'-hydroxy-4'-methoxy-benzyl)-2-methyl-6,7-methylendioxy-1,2,3,4-tetrahydroisochinolin

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(2'-Brom-3'-hydroxy-4'-methoxy-benzyl)-2-methyl-6,7-methylendioxy-1,2,3,4-tetrahydroisochinolin

There total 8 articles about 1-(2'-Brom-3'-hydroxy-4'-methoxy-benzyl)-2-methyl-6,7-methylendioxy-1,2,3,4-tetrahydroisochinolin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 116861-71-3
1-(2'-Brom-3'-benzyloxy-4'-methoxy-benzyl)-2-methyl-6,7-methylendioxy-1,2,3,4-tetrahydroisochinolin

: 116861-72-4
1-(2'-Brom-3'-hydroxy-4'-methoxy-benzyl)-2-methyl-6,7-methylendioxy-1,2,3,4-tetrahydroisochinolin

Guidance literature:: With hydrogenchloride; In ethanol; for 2h; Heating;
DOI:10.1002/ardp.19883210308

Reference yield:

: 38849-42-2
2-Brom-3-benzyloxy-4-methoxy-phenylessigsaeure

: 116861-72-4
1-(2'-Brom-3'-hydroxy-4'-methoxy-benzyl)-2-methyl-6,7-methylendioxy-1,2,3,4-tetrahydroisochinolin

Guidance literature:: Multi-step reaction with 5 steps

1: 54 percent / NaHCO₃ / xylene / 16 h / Heating

2: 82 percent / POCl₃ / toluene / 3 h / Heating

3: 84 percent / 5percent aq. NH₃ / CHCl₃ / 15 h / Heating

4: 98 percent / 1.) NaBH₄ / methanol / 1.) 50 deg C, 2.) room temp., 30 min

5: 84 percent / 32percent HCl / ethanol / 2 h / Heating

With hydrogenchloride; ammonium hydroxide; sodium tetrahydroborate; sodium hydrogencarbonate; trichlorophosphate; In methanol; ethanol; chloroform; toluene; xylene;
DOI:10.1002/ardp.19883210308

Reference yield:

: 2973-58-2
2-bromoisovanillin

: 116861-72-4
1-(2'-Brom-3'-hydroxy-4'-methoxy-benzyl)-2-methyl-6,7-methylendioxy-1,2,3,4-tetrahydroisochinolin

Guidance literature:: Multi-step reaction with 8 steps

2: 68 percent / SnCl₂*2H₂O, conc. HCl / acetic acid / 4 h / 100 °C

3: 87 percent / NaOH / methanol / 3 h / Heating

4: 54 percent / NaHCO₃ / xylene / 16 h / Heating

5: 82 percent / POCl₃ / toluene / 3 h / Heating

6: 84 percent / 5percent aq. NH₃ / CHCl₃ / 15 h / Heating

7: 98 percent / 1.) NaBH₄ / methanol / 1.) 50 deg C, 2.) room temp., 30 min

8: 84 percent / 32percent HCl / ethanol / 2 h / Heating

With hydrogenchloride; ammonium hydroxide; sodium hydroxide; sodium tetrahydroborate; sodium hydrogencarbonate; tin(ll) chloride; trichlorophosphate; In methanol; ethanol; chloroform; acetic acid; toluene; xylene;
DOI:10.1002/ardp.19883210308