Methyl 5-acetamido-3,5-dideoxy-β-D-glycero-D-galacto-2-nonulopyranosonate

Base Information

• Chemical Name: Methyl 5-acetamido-3,5-dideoxy-β-D-glycero-D-galacto-2-nonulopyranosonate
• CAS No.: 119241-61-1
• Molecular Formula: C₁₂H₂₁NO₉
• Molecular Weight: 323.3
• Mol file: 119241-61-1.mol

Synonyms:Methyl 5-acetamido-3,5-dideoxy-β-D-glycero-D-galacto-2-nonulopyranosonate

Chemical Property of Methyl 5-acetamido-3,5-dideoxy-β-D-glycero-D-galacto-2-nonulopyranosonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methyl 5-acetamido-3,5-dideoxy-β-D-glycero-D-galacto-2-nonulopyranosonate

There total 55 articles about Methyl 5-acetamido-3,5-dideoxy-β-D-glycero-D-galacto-2-nonulopyranosonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + sialic acid (489-46-3,6813-81-6,14120-72-0,19342-33-7,21646-00-4,82349-00-6,99395-98-9,99395-99-0,99396-00-6,102734-10-1,140671-47-2,140850-42-6,140850-43-7,140850-44-8,145375-13-9) → (2R,3R,4S)-3-acetamido-4-hydroxy-2-((1R,2R)-1,2,3-trihydroxypropyl)-3,4-dihydro-2H-pyran-6-carboxylic acid (22900-11-4,100678-43-1,109121-98-4,109122-00-1,119241-60-0,119241-61-1,119241-62-2,20298-35-5)

Guidance literature:

With IR(H⁺)resin; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.tetlet.2012.08.077

Reference yield: 100.0%

methanol (67-56-1) + N-acetyl neuraminic acid (6813-81-6,14120-72-0,19342-33-7,21646-00-4,82349-00-6,99395-98-9,99395-99-0,99396-00-6,102734-10-1,489-46-3,140671-47-2,140850-42-6,140850-43-7,140850-44-8,145375-13-9) → N-acetylneuraminic acid methyl ester (20298-35-5,22900-11-4,100678-43-1,109121-98-4,109122-00-1,119241-60-0,119241-61-1,119241-62-2)

Guidance literature:

With IR₁₂₀(H+); for 15h;

DOI:10.1055/s-2008-1072649

Reference yield: 100.0%

N-acetyl neuraminic acid (489-46-3,6813-81-6,14120-72-0,19342-33-7,21646-00-4,82349-00-6,99395-98-9,99395-99-0,99396-00-6,102734-10-1,140671-47-2,140850-42-6,140850-43-7,140850-44-8,145375-13-9) → methyl (4S,5R,6S)-5-acetamido-2,4-dihydroxy-6-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydro-2H-pyran-2-carboxylate (20298-35-5,22900-11-4,100678-43-1,109121-98-4,109122-00-1,119241-60-0,119241-61-1,119241-62-2)

Guidance literature:

With AG 50W-x8; In methanol; at 45 ℃;

upstream raw materials:

diazomethane

N-acetylneuraminic acid

methanol

N-acetyl neuraminic acid

Downstream raw materials:

N-acetylneuraminic acid methyl ester

N-acetyl-4,7,8,9-tetra-O-acetyl-2-chloro-2-deoxyneuraminic acid methyl ester

methyl (methyl 5-amino-3,5-dideoxy-β-D-glycero-D-galacto-2-nonulopyranosid)onate

methyl 5-acetamido-9-O-benzoyl-3,5-dideoxy-D-glycero-β-D-galacto-2-nonulopyranosylonate