(2-hydroxymethylphenyl)cyclobutylcarbinol

Base Information

Chemical Name:(2-hydroxymethylphenyl)cyclobutylcarbinol
CAS No.:1043927-22-5
Molecular Formula:C₁₂H₁₆O₂
Molecular Weight:192.258
Hs Code.:

Synonyms:(2-hydroxymethylphenyl)cyclobutylcarbinol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2-hydroxymethylphenyl)cyclobutylcarbinol

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Technology Process of (2-hydroxymethylphenyl)cyclobutylcarbinol

There total 1 articles about (2-hydroxymethylphenyl)cyclobutylcarbinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 4397-00-6
rac-(cyclobutyl)(phenyl)methanol

: 1043927-22-5
(2-hydroxymethylphenyl)cyclobutylcarbinol

Guidance literature:: rac-(cyclobutyl)(phenyl)methanol; With n-butyllithium; In diethyl ether; at 0 ℃; Reflux; Inert atmosphere;

formaldehyd; In diethyl ether; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1039/b801206g

Reference yield: 80.0%

: 1043927-22-5
(2-hydroxymethylphenyl)cyclobutylcarbinol

: 18162-48-6
tert-butyldimethylsilyl chloride

: 1043927-23-6
(2-tert-butyldimethylsilyloxymethylphenyl)cyclobutylcarbinol

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide; at -10 ℃; for 2.33333h; regioselective reaction; Inert atmosphere;
DOI:10.1039/b801206g