(3α)-3-Deoxy-3-chlorogalanthaMine

Base Information

Chemical Name:(3α)-3-Deoxy-3-chlorogalanthaMine
CAS No.:146274-40-0
Molecular Formula:C₁₇H₂₀ClNO₂
Molecular Weight:305.804
Hs Code.:
Mol file:146274-40-0.mol

Synonyms:(-)-(4aα,6β)-6-chloro-4a-5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-e,f][2]benzazepin

Suppliers and Price of (3α)-3-Deoxy-3-chlorogalanthaMine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(3α)-3-Deoxy-3-chlorogalanthamine
50mg
$ 1320.00

Medical Isotopes, Inc.
(3α)-3-Deoxy-3-chlorogalanthamine
50 mg
$ 2200.00

Medical Isotopes, Inc.
(3α)-3-Deoxy-3-chlorogalanthamine
5 mg
$ 650.00

Total 1 raw suppliers

Chemical Property of (3α)-3-Deoxy-3-chlorogalanthaMine

Chemical Property:

Storage Temp.:Refrigerator
Solubility.:Chloroform, Dichloromethane, Ethyl Acetate, Methanol

Purity/Quality:: (3α)-3-Deoxy-3-chlorogalanthamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Galanthamine (G188500) derivative, a cortical acetylcholinesterase (AChE) inhibitor.

Technology Process of (3α)-3-Deoxy-3-chlorogalanthaMine

There total 2 articles about (3α)-3-Deoxy-3-chlorogalanthaMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 357-70-0
Galantamine

: 146274-40-0
(-)-(4aα,6β)-6-chloro-4a-5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-e,f][2]benzazepin

Guidance literature:: With thionyl chloride; In toluene; at 55 ℃; for 2h;
DOI:10.1691/ph.2007.6.6661

Reference yield:

: 1953-04-4,98125-73-6,193146-85-9
Galantamine hydrobromide

: 146274-40-0
(-)-(4aα,6β)-6-chloro-4a-5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-e,f][2]benzazepin

Guidance literature:: With pyridine; methanesulfonyl chloride; In dichloromethane;
DOI:10.1021/ja054449+

Reference yield: 37.0%

: 5707-04-0
Phenylselenyl chloride

: 146274-40-0
(-)-(4aα,6β)-6-chloro-4a-5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-e,f][2]benzazepin

: C₂₃H₂₆ClNO₂Se

: 312920-69-7
(-)-3-deoxygalanthamine

Guidance literature:: (-)-(4aα,6β)-6-chloro-4a-5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-e,f][2]benzazepin; With lithium triethylborohydride; In tetrahydrofuran; at 40 ℃; for 8h;

Phenylselenyl chloride; In dichloromethane; at 40 ℃; for 2h;
DOI:10.1021/ja054449+