Technology Process of 4,4'-([2,2'-bipyridine]-4,4'-diyl)diphenol
There total 5 articles about 4,4'-([2,2'-bipyridine]-4,4'-diyl)diphenol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate;
In
1,4-dioxane; water;
at 110 ℃;
for 4h;
Inert atmosphere;
DOI:10.1016/j.bmc.2018.10.034
- Guidance literature:
-
Multi-step reaction with 3 steps
1: acetyl chloride; acetic acid / 14 h / 25 - 100 °C / Inert atmosphere
2: phosphorus trichloride / chloroform / 20 h / 65 °C / Inert atmosphere
3: potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / water; 1,4-dioxane / 4 h / 110 °C / Inert atmosphere
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate; acetic acid; acetyl chloride; phosphorus trichloride;
In
1,4-dioxane; chloroform; water;
3: |Suzuki Coupling;
DOI:10.1016/j.bmc.2018.10.034
- Guidance literature:
-
Multi-step reaction with 5 steps
1: dihydrogen peroxide; acetic acid / water / 15 h / 70 °C / Inert atmosphere
2: sulfuric acid; nitric acid / 20 h / 0 - 100 °C / Inert atmosphere
3: acetyl chloride; acetic acid / 14 h / 25 - 100 °C / Inert atmosphere
4: phosphorus trichloride / chloroform / 20 h / 65 °C / Inert atmosphere
5: potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / water; 1,4-dioxane / 4 h / 110 °C / Inert atmosphere
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sulfuric acid; dihydrogen peroxide; nitric acid; potassium carbonate; acetic acid; acetyl chloride; phosphorus trichloride;
In
1,4-dioxane; chloroform; water;
5: |Suzuki Coupling;
DOI:10.1016/j.bmc.2018.10.034
