N-methyl-3-(methyloxy)-N-(3(RS)-pyrrolidinylmethyl)-4-biphenylcarboxamide

Base Information

Chemical Name:N-methyl-3-(methyloxy)-N-(3(RS)-pyrrolidinylmethyl)-4-biphenylcarboxamide
CAS No.:1426095-69-3
Molecular Formula:C₂₀H₂₄N₂O₂
Molecular Weight:324.423
Hs Code.:

Synonyms:N-methyl-3-(methyloxy)-N-(3(RS)-pyrrolidinylmethyl)-4-biphenylcarboxamide

Suppliers and Price of N-methyl-3-(methyloxy)-N-(3(RS)-pyrrolidinylmethyl)-4-biphenylcarboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-methyl-3-(methyloxy)-N-(3(RS)-pyrrolidinylmethyl)-4-biphenylcarboxamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-methyl-3-(methyloxy)-N-(3(RS)-pyrrolidinylmethyl)-4-biphenylcarboxamide

There total 10 articles about N-methyl-3-(methyloxy)-N-(3(RS)-pyrrolidinylmethyl)-4-biphenylcarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: C₂₅H₃₂N₂O₄

: 1426095-69-3
N-methyl-3-(methyloxy)-N-(3(RS)-pyrrolidinylmethyl)-4-biphenylcarboxamide

Guidance literature:: C₂₅H₃₂N₂O₄; With hydrogenchloride; In tetrahydrofuran; water; for 0.166667h;

In water; pH=7;

Reference yield:

: 270912-72-6
tert-butyl 3-(aminomethyl)pyrrolidine-1-carboxylate

: 1426095-69-3
N-methyl-3-(methyloxy)-N-(3(RS)-pyrrolidinylmethyl)-4-biphenylcarboxamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine; HATU / N,N-dimethyl-formamide / 18 h

2.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.17 h

2.2: 18 h

3.1: hydrogenchloride / tetrahydrofuran; water / 0.17 h

3.2: pH 7

With hydrogenchloride; triethylamine; HATU; lithium hexamethyldisilazane; In tetrahydrofuran; water; N,N-dimethyl-formamide;

Reference yield:

: 93138-61-5
C-(1-benzyl-pyrrolidin-3-yl)-methylamine

: 1426095-69-3
N-methyl-3-(methyloxy)-N-(3(RS)-pyrrolidinylmethyl)-4-biphenylcarboxamide

Guidance literature:: Multi-step reaction with 7 steps

1.1: dichloromethane / 12 h / 0 - 20 °C

2.1: palladium 10% on activated carbon; hydrogen; palladium(II) hydroxide; acetic acid / methanol / 48 h / 20 °C

3.1: triethylamine / methanol / 0.5 h / 0 °C

3.2: 24 h / 0 - 20 °C

4.1: sodium hydroxide / methanol; water / 3 h / 20 °C

5.1: triethylamine; HATU / N,N-dimethyl-formamide / 18 h

6.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.17 h

6.2: 18 h

7.1: hydrogenchloride / tetrahydrofuran; water / 0.17 h

7.2: pH 7

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; palladium(II) hydroxide; acetic acid; triethylamine; HATU; sodium hydroxide; lithium hexamethyldisilazane; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;