(RS)-S-(3-nitrophenyl)-N-(isopropylcarbamoyl)-S-methyl-sulfoximide

Base Information

• Chemical Name: (RS)-S-(3-nitrophenyl)-N-(isopropylcarbamoyl)-S-methyl-sulfoximide
• CAS No.: 1002358-21-5
• Molecular Formula: C₁₁H₁₅N₃O₄S
• Molecular Weight: 285.324
• Mol file: 1002358-21-5.mol

Synonyms:(RS)-S-(3-nitrophenyl)-N-(isopropylcarbamoyl)-S-methyl-sulfoximide

Chemical Property of (RS)-S-(3-nitrophenyl)-N-(isopropylcarbamoyl)-S-methyl-sulfoximide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (RS)-S-(3-nitrophenyl)-N-(isopropylcarbamoyl)-S-methyl-sulfoximide

There total 3 articles about (RS)-S-(3-nitrophenyl)-N-(isopropylcarbamoyl)-S-methyl-sulfoximide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

imino(methyl)(3-nitrophenyl)-λ6-sulfanone (22133-02-4) + Isopropyl isocyanate (1795-48-8) → (RS)-S-(3-nitrophenyl)-N-(isopropylcarbamoyl)-S-methyl-sulfoximide (1002358-21-5)

Guidance literature:

In toluene; at 20 - 104 ℃; for 111h;

Reference yield:

methyl 3-nitrophenyl sulfoxide (132016-29-6,146143-21-7,3272-42-2) → (RS)-S-(3-nitrophenyl)-N-(isopropylcarbamoyl)-S-methyl-sulfoximide (1002358-21-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium azide; sulfuric acid / dichloromethane / 24 h / 0 - 45 °C

1.2: 0 °C / pH 11

2.1: toluene / 111 h / 20 - 104 °C

With sodium azide; sulfuric acid; In dichloromethane; toluene;

Reference yield:

1-(methylsulfanyl)-3-nitrobenzene (2524-76-7) → (RS)-S-(3-nitrophenyl)-N-(isopropylcarbamoyl)-S-methyl-sulfoximide (1002358-21-5)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sulfuryl dichloride / dichloromethane / 4 h / -60 - -20 °C

2.1: sodium azide; sulfuric acid / dichloromethane / 24 h / 0 - 45 °C

2.2: 0 °C / pH 11

3.1: toluene / 111 h / 20 - 104 °C

With sodium azide; sulfuryl dichloride; sulfuric acid; In dichloromethane; toluene;

upstream raw materials:

imino(methyl)(3-nitrophenyl)-λ⁶-sulfanone

Isopropyl isocyanate

1-(methylsulfanyl)-3-nitrobenzene

methyl 3-nitrophenyl sulfoxide

Downstream raw materials:

(RS)-S-(3-aminophenyl)-N-(isopropylcarbamoyl)-S-methylsulfoximide