2-Hydroxy-5-methylpyrazine

Base Information

Chemical Name:2-Hydroxy-5-methylpyrazine
CAS No.:20721-17-9
Molecular Formula:C5H6N2O
Molecular Weight:110.115
Hs Code.:2933990090
NSC Number:143658
UNII:EX039G48ZE
DSSTox Substance ID:DTXSID70174787
Nikkaji Number:J51.191I
Wikidata:Q27277402
Mol file:20721-17-9.mol

Synonyms:2-Hydroxy-5-methylpyrazine;20721-17-9;5-methylpyrazin-2-ol;5-Methylpyrazin-2(1H)-one;2(1H)-Pyrazinone, 5-methyl-;Pyrazinol, 5-methyl-;5-Methyl-2(1H)-pyrazone;5-methyl-1H-pyrazin-2-one;Pyrazine, 2-hydroxy-5-methyl-;5-methylpyrazinol;5-Methyl-2(1H)-pyrazinone;EX039G48ZE;MFCD19216543;NSC-143658;NSC 143658;UNII-EX039G48ZE;5-methyl-pyrazinone;NSC143658;5-hydroxy-2-methylpyrazine;5-METHYL-2-PYRAZINOL;SCHEMBL752334;DTXSID70174787;BCP16191;5-methyl-1,2-dihydropyrazin-2-one;AKOS006349280;AKOS015856433;AM84718;CS-W008795;GS-5795;SY027652;3,4-DIHYDRO-6-METHYL-3-OXOPYRAZINE;FT-0650138;EN300-86098;A814833;W-206547;Q27277402

Suppliers and Price of 2-Hydroxy-5-methylpyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Methyl-2(1H)-pyrazinone
2.5g
$ 1260.00

SynQuest Laboratories
2-Hydroxy-5-methylpyrazine
1 g
$ 224.00

SynQuest Laboratories
2-Hydroxy-5-methylpyrazine
5 g
$ 600.00

Medical Isotopes, Inc.
5-Methyl-2(1H)-pyrazinone
250 mg
$ 650.00

Medical Isotopes, Inc.
5-Methyl-2(1H)-pyrazinone
2.5 g
$ 2200.00

Matrix Scientific
2-Hydroxy-5-methylpyrazine 95+%
5g
$ 1197.00

Matrix Scientific
2-Hydroxy-5-methylpyrazine 95+%
1g
$ 275.00

Crysdot
5-Methylpyrazin-2(1H)-one 98%
1g
$ 99.00

Chemenu
5-Methylpyrazin-2(1H)-one 95%+
5g
$ 299.00

Chemenu
5-Methylpyrazin-2(1H)-one 95%+
1g
$ 106.00

Total 37 raw suppliers

Chemical Property of 2-Hydroxy-5-methylpyrazine

Chemical Property:

Vapor Pressure:3.41E-06mmHg at 25°C
Melting Point:68-69 °C(Solv: ethyl ether (60-29-7))
Refractive Index:1.576
Boiling Point:376.2 °C at 760 mmHg
PKA:11.72±0.40(Predicted)
Flash Point:181.3 °C
PSA：46.01000
Density:1.22 g/cm³
LogP:0.49060
Storage Temp.:2-8°C
XLogP3:-0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:110.048012819
Heavy Atom Count:8
Complexity:169

Purity/Quality:

97% ^*data from raw suppliers

5-Methyl-2(1H)-pyrazinone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CNC(=O)C=N1
Uses 5-Methyl-2(1H)-pyrazinone is a useful synthetic intermediate. it is a derivative of 2-Hydroxypyrazine (H952710) which is used in the synthesis of potential antioxidants. 2-Hydroxypyrazine (H952710) is also used in the preparation of antibacterial agents as 2-substituted pyrazine derivatives.

Technology Process of 2-Hydroxy-5-methylpyrazine

There total 6 articles about 2-Hydroxy-5-methylpyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 1-benzyloxy-5-methyl-2(1H)-pyrazinone

: 20721-17-9
5-methyl-2(1H)-pyrazinone

Guidance literature:: In benzene; for 1.5h; Irradiation;
DOI:10.3987/com-96-7392

Reference yield:

: 131543-46-9,107-22-2
Glyoxal

: 33208-99-0
(S)-alaninamide hydrochloride

: 20721-17-9
2-hydroxy-5-methylpyrazine

Guidance literature:: Glyoxal; (S)-alaninamide hydrochloride; With sodium hydroxide; In methanol; water; at -40 - 20 ℃; for 18.0833h;

With hydrogenchloride; sodium hydrogencarbonate; In methanol; water; at 0 - 20 ℃; for 0.416667h;