2,3,4,9-Tetrahydrothiopyrano(2,3-b)indole-4-methylamine

Base Information

Chemical Name:2,3,4,9-Tetrahydrothiopyrano(2,3-b)indole-4-methylamine
CAS No.:73425-49-7
Molecular Formula:C12H14N2S
Molecular Weight:218.318
Hs Code.:
DSSTox Substance ID:DTXSID60994153

Synonyms:2,3,4,9-Tetrahydrothiopyrano(2,3-b)indole-4-methylamine;73425-49-7;4-(Aminomethyl)-2,3,4,9-tetrahydrothiopyrano(2,3-b)indole;Thiopyrano(2,3-b)indole-4-methylamine, 2,3,4,9-tetrahydro-;Thiopyrano(2,3-b)indole, 2,3,4,9-tetrahydro-4-(aminomethyl)-;SCHEMBL11386107;DTXSID60994153;MPNKHPNCBKDIDY-UHFFFAOYSA-N;LS-153273;4-aminomethyl-2,3,4,9-tetrahydrothiopyrano[2,3-b]indole;1-(2,3,4,9-Tetrahydrothiopyrano[2,3-b]indol-4-yl)methanamine

Suppliers and Price of 2,3,4,9-Tetrahydrothiopyrano(2,3-b)indole-4-methylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2,3,4,9-Tetrahydrothiopyrano(2,3-b)indole-4-methylamine

Chemical Property:

Vapor Pressure:4.96E-07mmHg at 25°C
Boiling Point:413°C at 760 mmHg
Flash Point:203.6°C
Density:1.262g/cm³
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:218.08776963
Heavy Atom Count:15
Complexity:234

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CSC2=C(C1CN)C3=CC=CC=C3N2

Technology Process of 2,3,4,9-Tetrahydrothiopyrano(2,3-b)indole-4-methylamine

There total 5 articles about 2,3,4,9-Tetrahydrothiopyrano(2,3-b)indole-4-methylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 73424-94-9
4-cyano-2,3,4,9-tetrahydrothiopyrano<2,3-b>indole

: 73425-49-7
4-aminomethyl-2,3,4,9-tetrahydrothiopyrano<2,3-b>indole

Guidance literature:: With sodium hydroxide; lithium aluminium tetrahydride; aluminium trichloride; In diethyl ether; for 2h; Ambient temperature;
DOI:10.1248/cpb.32.872

Reference yield:

: 59-48-3
2-oxoindole

: 73425-49-7
4-aminomethyl-2,3,4,9-tetrahydrothiopyrano<2,3-b>indole

Guidance literature:: Multi-step reaction with 4 steps

1: P₂S₅

2: 98 percent / K₂CO₃ / acetone / 3 h / Ambient temperature

3: 1.) Et₃N / 1.) EtOH, reflux, 1 h; 2.) EtOH, H₂O, reflux, 2 h;

4: 69 percent / 1) AlCl₃, LiAlH₄; 2.) aq. NaOH / diethyl ether / 2 h / Ambient temperature

With sodium hydroxide; lithium aluminium tetrahydride; aluminium trichloride; tetraphosphorus decasulfide; potassium carbonate; triethylamine; In diethyl ether; acetone;
DOI:10.1248/cpb.32.872

Reference yield:

: 73424-93-8
indole-2-yl-prop-2-ynyl sulfide

: 73425-49-7
4-aminomethyl-2,3,4,9-tetrahydrothiopyrano<2,3-b>indole

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Et₃N / 1.) EtOH, reflux, 1 h; 2.) EtOH, H₂O, reflux, 2 h;

2: 69 percent / 1) AlCl₃, LiAlH₄; 2.) aq. NaOH / diethyl ether / 2 h / Ambient temperature

With sodium hydroxide; lithium aluminium tetrahydride; aluminium trichloride; triethylamine; In diethyl ether;
DOI:10.1248/cpb.32.872