(S)-N^α-phthaloyl-O-benzyltyrosine chloride

Base Information

Chemical Name:(S)-N^α-phthaloyl-O-benzyltyrosine chloride
CAS No.:88036-14-0
Molecular Formula:C₂₄H₁₈ClNO₄
Molecular Weight:419.864
Hs Code.:

(S)-N<sup>α</sup>-phthaloyl-O-benzyltyrosine chloride

Synonyms:(S)-N^α-phthaloyl-O-benzyltyrosine chloride

Suppliers and Price of (S)-N^α-phthaloyl-O-benzyltyrosine chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-N^α-phthaloyl-O-benzyltyrosine chloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-N^α-phthaloyl-O-benzyltyrosine chloride

There total 1 articles about (S)-N^α-phthaloyl-O-benzyltyrosine chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 2130-97-4
(S)-N^α-phthaloyl-O-benzyltyrosine

: 88036-14-0
(S)-N^α-phthaloyl-O-benzyltyrosine chloride

Guidance literature:: With phosphorus pentachloride; In benzene; at 50 - 55 ℃; for 1.5h;
DOI:10.1021/jo000530d

Reference yield: 73.0%

: 88036-14-0
(S)-N^α-phthaloyl-O-benzyltyrosine chloride

: 56-40-6,18875-39-3,25718-94-9
glycine

: 306775-45-1
(S)-N^α-phthaloyl-O-benzyltyrosinylglycine

Guidance literature:: With sodium carbonate; In water; acetone; at 20 ℃; for 1h;
DOI:10.1021/jo000530d

Reference yield:

: 88036-14-0
(S)-N^α-phthaloyl-O-benzyltyrosine chloride

: 88036-24-2
4,7-dioxo-9-(4-hydroxyphenyl)-8(S)-<<(2,2,2-trichloroethoxy)carbonyl>amino>nonanoyl-L-phenylalanyl-L-leucine

Guidance literature:: Multi-step reaction with 11 steps

1: 1.) Mg / 1.) THF, 40 deg C, 45 min, 2.) THF, RT, 1 h

2: 64.5 percent / p-toluenesulfonic acid / toluene / 6 h

3: 76.9 percent / p-toluenesulfonic acid / acetone / 32 h / Ambient temperature

4: 1.) Mg / 1.) THF, 40 deg C, 45 min, 2.) THF, RT, 15 min

5: 99.3 percent / hydrazine / ethanol / 15 h / Heating

6: N,N-diisopropylethylamine / CH₂Cl₂ / 0.25 h / 0 °C

7: CrO₃, 35percent H₂SO₄ / acetone / 0.5 h / 0 °C

8: 55.9 percent / 1-hydroxybenzotriazole, Et₃N, dicyclohexylcarbodiimide (DCC) / CH₂Cl₂ / 64 h / Ambient temperature

9: 62.6 percent / 1 N aq. NaOH / tetrahydrofuran / 1.5 h

10: 50.9 percent / H₂ / 10percent Pd/C / acetic acid / 6.5 h / 760 Torr / Ambient temperature

11: 75.1 percent / aq. trifluoroacetic acid / 6 h / Ambient temperature

With chromium(VI) oxide; sodium hydroxide; sulfuric acid; hydrogen; benzotriazol-1-ol; toluene-4-sulfonic acid; magnesium; triethylamine; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; trifluoroacetic acid; hydrazine; palladium on activated charcoal; In tetrahydrofuran; ethanol; dichloromethane; acetic acid; acetone; toluene;
DOI:10.1021/jm00368a003