C₁₉H₃₁BO₄Si

Base Information

• Chemical Name: C₁₉H₃₁BO₄Si
• CAS No.: 1448449-55-5
• Molecular Formula: C₁₉H₃₁BO₄Si
• Molecular Weight: 362.349
• Mol file: 1448449-55-5.mol

Synonyms:C₁₉H₃₁BO₄Si

Chemical Property of C₁₉H₃₁BO₄Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₉H₃₁BO₄Si

There total 3 articles about C₁₉H₃₁BO₄Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

5-hydroxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde (1038827-60-9) + tert-butyldimethylsilyl chloride (18162-48-6) → C19H31BO4Si (1448449-55-5)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1039/c3ob40962g

Reference yield:

2-bromo-5-hydroxybenzaldehyde (2973-80-0) → C19H31BO4Si (1448449-55-5)

Guidance literature:

Multi-step reaction with 2 steps

1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 1,4-dioxane / 2 h / 100 °C / Inert atmosphere

2: 1H-imidazole / N,N-dimethyl-formamide / 2 h / 20 °C / Inert atmosphere

With 1H-imidazole; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In 1,4-dioxane; N,N-dimethyl-formamide; 1: |Miyaura Borylation Reaction;

DOI:10.1039/c3ob40962g

Reference yield:

bis(pinacol)diborane (73183-34-3) → C19H31BO4Si (1448449-55-5)

Guidance literature:

Multi-step reaction with 2 steps

1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 1,4-dioxane / 2 h / 100 °C / Inert atmosphere

2: 1H-imidazole / N,N-dimethyl-formamide / 2 h / 20 °C / Inert atmosphere

With 1H-imidazole; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In 1,4-dioxane; N,N-dimethyl-formamide; 1: |Miyaura Borylation Reaction;

DOI:10.1039/c3ob40962g

upstream raw materials:

5-hydroxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde

tert-butyldimethylsilyl chloride

2-bromo-5-hydroxybenzaldehyde

bis(pinacol)diborane

Downstream raw materials:

C₃₂H₅₁BO₄Si₂

C₂₀H₂₃BO₄

2-[(1E)-2-(4-hydroxyphenyl)ethenyl]-1,4-benzenediol

C₁₄H₁₀O₃