methyl (2S)-6-amino-2-((4-aminophenylsulfonyl)(3-methylbutyl)amino)hexanoate

Base Information

• Chemical Name: methyl (2S)-6-amino-2-((4-aminophenylsulfonyl)(3-methylbutyl)amino)hexanoate
• CAS No.: 748186-99-4
• Molecular Formula: C₁₈H₃₁N₃O₄S
• Molecular Weight: 385.528

Synonyms:methyl (2S)-6-amino-2-((4-aminophenylsulfonyl)(3-methylbutyl)amino)hexanoate

Chemical Property of methyl (2S)-6-amino-2-((4-aminophenylsulfonyl)(3-methylbutyl)amino)hexanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl (2S)-6-amino-2-((4-aminophenylsulfonyl)(3-methylbutyl)amino)hexanoate

There total 7 articles about methyl (2S)-6-amino-2-((4-aminophenylsulfonyl)(3-methylbutyl)amino)hexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methanol (67-56-1) + (S)-6-Amino-2-[(4-amino-benzenesulfonyl)-(3-methyl-butyl)-amino]-hexanoic acid (748186-98-3) → methyl (2S)-6-amino-2-((4-aminophenylsulfonyl)(3-methylbutyl)amino)hexanoate (748186-99-4)

Guidance literature:

With chloro-trimethyl-silane; at 20 ℃;

DOI:10.1016/j.bmcl.2004.05.049

Reference yield:

2-aminocaprolactam (21568-87-6) → methyl (2S)-6-amino-2-((4-aminophenylsulfonyl)(3-methylbutyl)amino)hexanoate (748186-99-4)

Guidance literature:

Multi-step reaction with 4 steps

1: 89 percent / STAB / CH₂Cl₂

2: 88 percent / TEA / ethyl acetate

3: 99 percent / aq. HCl / Heating

4: 95 percent / TMS-Cl / 20 °C

With hydrogenchloride; chloro-trimethyl-silane; TEA; sodium tris(acetoxy)borohydride; In dichloromethane; ethyl acetate;

DOI:10.1016/j.bmcl.2004.05.049

Reference yield:

methyl (2S)-6-benzyloxycarbonylamino-2-((3-methylbutyl)(4-nitrophenylsulfonyl)amino)hexanoate (1138018-01-5) → methyl (2S)-6-amino-2-((4-aminophenylsulfonyl)(3-methylbutyl)amino)hexanoate (748186-99-4)

Guidance literature:

With hydrogen; palladium(II) hydroxide/carbon; In methanol; for 2h; under 760.051 Torr;

upstream raw materials:

methanol

(S)-6-Amino-2-[(4-amino-benzenesulfonyl)-(3-methyl-butyl)-amino]-hexanoic acid

p-acetylaminobenzenesulfonyl chloride

isovaleraldehyde

Downstream raw materials:

methyl 2-(((4-aminophenyl)sulfonyl)(3-methylbutyl)amino)-6-(((2S)-2-((methoxycarbonyl)amino)-3,3-diphenylpropanoyl)amino)hexanoate

{5-[(4-amino-benzenesulfonyl)-(3-methyl-butyl)-amino]-6-hydroxy-hexyl}-carbamic acid 9H-fluoren-9-ylmethyl ester

4-amino-N-(5-amino-1-hydroxymethyl-pentyl)-N-(3-methyl-butyl)-benzenesulfonamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 748186-99-4 methyl (2S)-6-amino-2-((4-aminophenylsulfonyl)(3-methylbutyl)amino)hexanoate

Send

Send

Metric Ton KG G Pound L ML

Send

Send