(+/-)-2-Brom-2-<2-(2,5-dioxo-1-pyrrolidinyl)phenyl>essigsaeure-methylester

Base Information

Chemical Name:(+/-)-2-Brom-2-<2-(2,5-dioxo-1-pyrrolidinyl)phenyl>essigsaeure-methylester
CAS No.:90163-15-8
Molecular Formula:C₁₃H₁₂BrNO₄
Molecular Weight:326.147
Hs Code.:

Synonyms:(+/-)-2-Brom-2-<2-(2,5-dioxo-1-pyrrolidinyl)phenyl>essigsaeure-methylester

Suppliers and Price of (+/-)-2-Brom-2-<2-(2,5-dioxo-1-pyrrolidinyl)phenyl>essigsaeure-methylester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (+/-)-2-Brom-2-<2-(2,5-dioxo-1-pyrrolidinyl)phenyl>essigsaeure-methylester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (+/-)-2-Brom-2-<2-(2,5-dioxo-1-pyrrolidinyl)phenyl>essigsaeure-methylester

There total 7 articles about (+/-)-2-Brom-2-<2-(2,5-dioxo-1-pyrrolidinyl)phenyl>essigsaeure-methylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 98911-39-8
2-[2-(2,5-Dioxo-1-pyrrolidinyl)phenyl]essigsaeure-methylester

: 90163-15-8
(+/-)-2-Brom-2-<2-(2,5-dioxo-1-pyrrolidinyl)phenyl>essigsaeure-methylester

Guidance literature:: With N-Bromosuccinimide; In tetrachloromethane; for 1.25h; Heating; Irradiation;
DOI:10.1002/jlac.198519850711

Reference yield:

: 3740-52-1
2-(2-nitrophenyl)acetic acid

: 90163-15-8
(+/-)-2-Brom-2-<2-(2,5-dioxo-1-pyrrolidinyl)phenyl>essigsaeure-methylester

Guidance literature:: Multi-step reaction with 7 steps

1: 88 percent / HClO₄ / 40 h / Ambient temperature

2: H₂ / 10percent Pd/C / ethyl acetate / 4 h / 0 - 5 °C / 735.5 Torr

3: dioxane; pyridine / 14 h / 5 °C

4: 1) 1-hydroxybenzotriazole, 2) DCC / 1) CH₂Cl₂, 20 min, 2) 15 h, r.t.

5: 96 percent / p-toluene sulfonic acid / benzene / 2 h / Heating

6: 78 percent / diethyl ether; methanol / 2 h / Ambient temperature

7: 96 percent / NBS / CCl₄ / 1.25 h / Heating; Irradiation

With N-Bromosuccinimide; perchloric acid; hydrogen; benzotriazol-1-ol; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide; palladium on activated charcoal; In 1,4-dioxane; pyridine; methanol; tetrachloromethane; diethyl ether; ethyl acetate; benzene;
DOI:10.1002/jlac.198519850711

Reference yield:

: 98911-33-2
2-(2-Nitrophenyl)essigsaeure-tert-butylester

: 90163-15-8
(+/-)-2-Brom-2-<2-(2,5-dioxo-1-pyrrolidinyl)phenyl>essigsaeure-methylester

Guidance literature:: Multi-step reaction with 6 steps

1: H₂ / 10percent Pd/C / ethyl acetate / 4 h / 0 - 5 °C / 735.5 Torr

2: dioxane; pyridine / 14 h / 5 °C

3: 1) 1-hydroxybenzotriazole, 2) DCC / 1) CH₂Cl₂, 20 min, 2) 15 h, r.t.

4: 96 percent / p-toluene sulfonic acid / benzene / 2 h / Heating

5: 78 percent / diethyl ether; methanol / 2 h / Ambient temperature

6: 96 percent / NBS / CCl₄ / 1.25 h / Heating; Irradiation

With N-Bromosuccinimide; hydrogen; benzotriazol-1-ol; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide; palladium on activated charcoal; In 1,4-dioxane; pyridine; methanol; tetrachloromethane; diethyl ether; ethyl acetate; benzene;
DOI:10.1002/jlac.198519850711