C₂₄H₃₅NO₃

Base Information

• Chemical Name: C₂₄H₃₅NO₃
• CAS No.: 1072091-41-8
• Molecular Formula: C₂₄H₃₅NO₃
• Molecular Weight: 385.547
• Mol file: 1072091-41-8.mol

Synonyms:C₂₄H₃₅NO₃

Chemical Property of C₂₄H₃₅NO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₃₅NO₃

There total 18 articles about C₂₄H₃₅NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C24H34INO3 (1072091-40-7) → C24H35NO3 (1072091-41-8)

Guidance literature:

C₂₄H₃₄INO₃; With chromium dichloride; nickel dichloride; In N,N-dimethyl-formamide; at 20 ℃; for 13h;

With water; L-serine sodium salt; In N,N-dimethyl-formamide;

Reference yield:

ethyl 7-hydroxyheptanoate (6149-48-0) → C24H35NO3 (1072091-41-8)

Guidance literature:

Multi-step reaction with 7 steps

1: 1H-imidazole / N,N-dimethyl-formamide / 0.5 h / 20 °C

2: lithium hydroxide; water / tetrahydrofuran; methanol / 1.5 h / 20 °C

3: hydrogenchloride / water

4: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; diisopropylamine / N,N-dimethyl-formamide / 24 h / 20 °C

5: tetrabutyl ammonium fluoride / tetrahydrofuran / 19.5 h / 20 °C

6: Dess-Martin periodane / dichloromethane / 2 h / 20 °C

7: chromium dichloride / nickel dichloride / N,N-dimethyl-formamide / 13 h / 20 °C

With 1H-imidazole; chromium dichloride; hydrogenchloride; lithium hydroxide; tetrabutyl ammonium fluoride; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; water; Dess-Martin periodane; diisopropylamine; nickel dichloride; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; 7: Nozaki-Hiyama-Kishi Coupling;

Reference yield:

ethyl 7-bromoheptanoate (29823-18-5) → C24H35NO3 (1072091-41-8)

Guidance literature:

Multi-step reaction with 8 steps

1: formic acid; triethylamine / 21 h / 50 °C

2: 1H-imidazole / N,N-dimethyl-formamide / 0.5 h / 20 °C

3: lithium hydroxide; water / tetrahydrofuran; methanol / 1.5 h / 20 °C

4: hydrogenchloride / water

5: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; diisopropylamine / N,N-dimethyl-formamide / 24 h / 20 °C

6: tetrabutyl ammonium fluoride / tetrahydrofuran / 19.5 h / 20 °C

7: Dess-Martin periodane / dichloromethane / 2 h / 20 °C

8: chromium dichloride / nickel dichloride / N,N-dimethyl-formamide / 13 h / 20 °C

With 1H-imidazole; chromium dichloride; hydrogenchloride; lithium hydroxide; formic acid; tetrabutyl ammonium fluoride; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; water; Dess-Martin periodane; triethylamine; diisopropylamine; nickel dichloride; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; 8: Nozaki-Hiyama-Kishi Coupling;

upstream raw materials:

C₂₄H₃₄INO₃

ethyl 7-hydroxyheptanoate

ethyl 7-bromoheptanoate

tert-butyl {(1S,2E)-4-(benzyloxy)-1-[(1R)-2-hydroxy-1-methylethyl]-2-methylbut-2-en-1-yl}carbamate

Downstream raw materials:

(9E,11S,12S)-12-[(1E)-3-benzyloxy-1-methylprop-1-en-1-yl]-8-{[tert-butyl(dimethyl)silyl]oxy}-1,1'-dimethylazacyclododec-9-en-2-one

C₁₈H₂₉NO₂

(2S,3S,4E)-1,3-dimethyl-2-[(1E)-1-methylbuta-1,3-dien-1-yl]-12-oxoazacylododec-4-en-6-yl acetate

(2S,3S,4E)-2-((1E,3E,5S)-6-{(2R,3R)-3-[(1R,2S)-2-hydroxy-1-methylbutyl]oxiran-2-yl}-1,5-dimethylhexa-1,3-dien-1-yl)-1,3-dimethyl-12-oxaazacyclododec-4-en-6-yl acetate