Technology Process of n-Heptin-(2)-ylphenylether
There total 3 articles about n-Heptin-(2)-ylphenylether which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
1-phenoxy-2-propyne;
With
n-butyllithium;
In
tetrahydrofuran;
at -78 ℃;
for 0.5h;
Inert atmosphere;
1-bromo-butane;
With
tetra-(n-butyl)ammonium iodide;
In
tetrahydrofuran;
at -78 - 23 ℃;
Inert atmosphere;
DOI:10.1021/ol202621g
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydride / N,N-dimethyl-aniline; mineral oil / 0.17 h / 23 °C / Inert atmosphere
1.2: 2 h / 23 °C / Inert atmosphere
2.1: n-butyllithium / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere
2.2: -78 - 23 °C / Inert atmosphere
With
n-butyllithium; sodium hydride;
In
tetrahydrofuran; N,N-dimethyl-aniline; mineral oil;
DOI:10.1021/ol202621g
- Guidance literature:
-
Phenyl-propargylether, Butylbromid, NH3;
