(1S,6S)-2,2-dimethyl-1-(2'-methoxycarbonyl-3'-oxobutyl)-6-methoxymethyloxycyclohexane

Base Information

Chemical Name:(1S,6S)-2,2-dimethyl-1-(2'-methoxycarbonyl-3'-oxobutyl)-6-methoxymethyloxycyclohexane
CAS No.:924884-78-6
Molecular Formula:C₁₆H₂₈O₅
Molecular Weight:300.395
Hs Code.:

Synonyms:(1S,6S)-2,2-dimethyl-1-(2'-methoxycarbonyl-3'-oxobutyl)-6-methoxymethyloxycyclohexane

Suppliers and Price of (1S,6S)-2,2-dimethyl-1-(2'-methoxycarbonyl-3'-oxobutyl)-6-methoxymethyloxycyclohexane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1S,6S)-2,2-dimethyl-1-(2'-methoxycarbonyl-3'-oxobutyl)-6-methoxymethyloxycyclohexane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1S,6S)-2,2-dimethyl-1-(2'-methoxycarbonyl-3'-oxobutyl)-6-methoxymethyloxycyclohexane

There total 4 articles about (1S,6S)-2,2-dimethyl-1-(2'-methoxycarbonyl-3'-oxobutyl)-6-methoxymethyloxycyclohexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 924884-77-5
(1S,6S)-(+)-2,2-dimethyl-1-iodomethyl-6-methoxymethyloxycyclohexane

: 105-45-3
acetoacetic acid methyl ester

: 924884-78-6
(1S,6S)-2,2-dimethyl-1-(2'-methoxycarbonyl-3'-oxobutyl)-6-methoxymethyloxycyclohexane

Guidance literature:: With sodium methylate; In methanol; at 60 - 90 ℃; for 13h;
DOI:10.1016/j.tetasy.2006.11.015

Reference yield:

: 6-hydroxy-2,2-dimethyl-cyclohexanecarboxylic acid methyl ester

: 924884-78-6
(1S,6S)-2,2-dimethyl-1-(2'-methoxycarbonyl-3'-oxobutyl)-6-methoxymethyloxycyclohexane

Guidance literature:: Multi-step reaction with 4 steps

1: 96 percent / N,N-diisopropylethylamine / dimethylformamide / 2.5 h / 80 °C

2: 97 percent / LiAlH₄ / diethyl ether / 1.5 h / 20 °C

3: 8.78 g / I₂; triphenylphosphine; imidazole / tetrahydrofuran / 7 h / 20 °C

4: 77 percent / NaOMe / methanol / 13 h / 60 - 90 °C

With 1H-imidazole; lithium aluminium tetrahydride; iodine; sodium methylate; N-ethyl-N,N-diisopropylamine; triphenylphosphine; In tetrahydrofuran; methanol; diethyl ether; N,N-dimethyl-formamide;
DOI:10.1016/j.tetasy.2006.11.015

Reference yield:

: 924884-76-4
(1R,6S)-(+)-2,2-dimethyl-1-hydroxymethyl-6-methoxymethyloxycyclohexane

: 924884-78-6
(1S,6S)-2,2-dimethyl-1-(2'-methoxycarbonyl-3'-oxobutyl)-6-methoxymethyloxycyclohexane

Guidance literature:: Multi-step reaction with 2 steps

1: 8.78 g / I₂; triphenylphosphine; imidazole / tetrahydrofuran / 7 h / 20 °C

2: 77 percent / NaOMe / methanol / 13 h / 60 - 90 °C

With 1H-imidazole; iodine; sodium methylate; triphenylphosphine; In tetrahydrofuran; methanol;
DOI:10.1016/j.tetasy.2006.11.015