Welcome to LookChem.com Sign In|Join Free
  • or

Encyclopedia

Unii-24P4O1J71F

Base Information Edit
  • Chemical Name:Unii-24P4O1J71F
  • CAS No.:688756-00-5
  • Molecular Formula:C23H20Cl2F3N5O5S
  • Molecular Weight:606.41
  • Hs Code.:
  • UNII:24P4O1J71F
  • Wikidata:Q27253866
  • Mol file:688756-00-5.mol
Unii-24P4O1J71F

Synonyms:BIRT-2584;UNII-24P4O1J71F;24P4O1J71F;BIRT 2584;688756-00-5;BIRT2584;SCHEMBL4017930;Q27253866;(S)-2-[(R)-7-(3,5-Dichloro-phenyl)-5-methyl-6-oxo-5-(4-trifluoromethoxy-benzyl)-6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonylamino]-propionamide;PROPANAMIDE, 2-((((3R)-1-(3,5-DICHLOROPHENYL)-2,3-DIHYDRO-3-METHYL-2-OXO-3-((4-(TRIFLUOROMETHOXY)PHENYL)METHYL)-1H-IMIDAZO(1,2-A)IMIDAZOL-5-YL)SULFONYL)AMINO)-, (2S)-

Suppliers and Price of Unii-24P4O1J71F
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
Total 0 raw suppliers
Chemical Property of Unii-24P4O1J71F Edit
Chemical Property:
  • XLogP3:4.4
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:10
  • Rotatable Bond Count:8
  • Exact Mass:605.0514298
  • Heavy Atom Count:39
  • Complexity:1030
Purity/Quality:
Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:
Useful:
  • Canonical SMILES:CC(C(=O)N)NS(=O)(=O)C1=CN=C2N1C(C(=O)N2C3=CC(=CC(=C3)Cl)Cl)(C)CC4=CC=C(C=C4)OC(F)(F)F
  • Isomeric SMILES:C[C@@H](C(=O)N)NS(=O)(=O)C1=CN=C2N1[C@](C(=O)N2C3=CC(=CC(=C3)Cl)Cl)(C)CC4=CC=C(C=C4)OC(F)(F)F
  • Recent EU Clinical Trials:One year follow-up of patients treated in Study 1206.5, a 12 week double-blind, randomised, placebo-controlled, modified dose-escalation trial to investigate safety, efficacy, and pharmacokinetics of BIRT 2584XX tablets at doses of 100,300 and 500 mg administered once daily in patients with moderate to severe psoriasis with a 12 week treatment extension for PASI 50 responders.
Technology Process of Unii-24P4O1J71F

There total 13 articles about Unii-24P4O1J71F which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
Multi-step reaction with 9 steps
1.1: water; sodium hydroxide / ethyl acetate / 0.5 h
1.2: 10.5 h / 17 - 23 °C / Reflux
1.3: 12 h / 50 °C
2.1: 3 h / 0 - 20 °C
3.1: 1.5 h / 0 - 5 °C
4.1: potassium hydroxide / isopropyl alcohol / 1 h / 60 °C
4.2: 3 h / 60 °C
5.1: 3 h / 60 °C
6.1: 2.5 h / 10 - 20 °C
6.2: 2 h / 40 - 50 °C
7.1: 1.5 h / 10 - 20 °C
8.1: 0.92 h / -15 - -5 °C
8.2: 0.75 h / -15 - -5 °C
8.3: 0.67 h / -5 °C
9.1: 6 h / -20 - 23 °C
With water; potassium hydroxide; sodium hydroxide; In ethyl acetate; isopropyl alcohol;
DOI:10.1021/op200175t
Post RFQ for Price