Miotine

Base Information

• Chemical Name: Miotine
• CAS No.: 4464-16-8
• Molecular Formula: C12H18N2O2
• Molecular Weight: 0
• Hs Code.: 2924299090
• UNII: 9Z3ZT09RRU
• DSSTox Substance ID: DTXSID10275489
• Nikkaji Number: J391.662F
• Wikipedia: Miotine
• Wikidata: Q6871576
• Metabolomics Workbench ID: 67754
• ChEMBL ID: CHEMBL1181675
• Mol file: 4464-16-8.mol

Synonyms:Miotine;Miotin;4464-16-8;9Z3ZT09RRU;Deethyl rivastigmine, (+/-)-;UNII-9Z3ZT09RRU;CHEBI:6943;C11763;3-(1-(Dimethylamino)ethyl)phenyl methylcarbamate;LS-50124;Phenol, 3-(1-(dimethylamino)ethyl)-, 1-(N-methylcarbamate);Carbamic acid, methyl-, m-(1-(dimethylamino)ethyl)phenyl ester;Phenol, 3-(1-(dimethylamino)ethyl)-, methylcarbamate (ester);3-[1-(dimethylamino)ethyl]phenyl methylcarbamate;Methylcarbamic acid [3-[1-(dimethylamino)ethyl]phenyl] ester;AC1L2FBX;AC1Q60SR;d-Miotine;l-Miotine;d-Miotin;l-Miotin;[3-[1-(dimethylamino)ethyl]phenyl] N-methylcarbamate;SureCN12043569;CHEMBL1181675;NIOSH/FB9832000;NIOSH/FB9833000;SCHEMBL12043569;BDBM10950;DTXSID10275489;LS-50125;FB98320000;FB98330000;[3-(1-dimethylaminoethyl)phenyl] N-methylcarbamate;3-[1-(dimethylamino)ethyl]phenyl N-methylcarbamate;Q6871576;Methylcarbamic acid[3-[1-(dimethylamino)ethyl]phenyl]ester;Carbamic acid, methyl-, m-(1-(dimethylamino)ethyl)phenyl ester, d-;Carbamic acid, methyl-, m-(1-(dimethylamino)ethyl)phenyl ester, l-;Phenol, 3-(1-(dimethylamino)ethyl)-, methylcarbamate (ester), d-;Phenol, 3-(1-(dimethylamino)ethyl)-, methylcarbamate (ester), l-

Chemical Property of Miotine

Chemical Property:

• PSA: 45.06000
• LogP: 2.23180
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 222.136827821
• Heavy Atom Count: 16
• Complexity: 231

Purity/Quality:

95%+ or 98%+ ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C1=CC(=CC=C1)OC(=O)NC)N(C)C

Technology Process of Miotine

There total 6 articles about Miotine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(3-methoxy)-phenylethanol (89691-63-4,120523-12-8,129940-69-8,23308-82-9) → methyl-carbamic acid-[3-(1-dimethylamino-ethyl)-phenyl ester] (4464-16-8)

Guidance literature:

Multi-step reaction with 3 steps

1: benzene; hydrogen bromide / und Eintragen des mit Benzol verduennten Reaktionsprodukts in eine Loesung von Dimethylamin in Benzol unter Kuehlung mit Kaeltemischung

2: hydrobromic acid

3: benzene

With hydrogen bromide; benzene;

Reference yield:

N,N-dimethyl-α-(m-methoxyphenyl)ethylamine (129052-92-2) → methyl-carbamic acid-[3-(1-dimethylamino-ethyl)-phenyl ester] (4464-16-8)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrobromic acid

2: benzene

With hydrogen bromide; benzene;

Reference yield:

3-methoxy-benzaldehyde (591-31-1) → methyl-carbamic acid-[3-(1-dimethylamino-ethyl)-phenyl ester] (4464-16-8)

Guidance literature:

Multi-step reaction with 4 steps

2: benzene; hydrogen bromide / und Eintragen des mit Benzol verduennten Reaktionsprodukts in eine Loesung von Dimethylamin in Benzol unter Kuehlung mit Kaeltemischung

3: hydrobromic acid

4: benzene

With hydrogen bromide; benzene;

upstream raw materials:

(+/-)-3-<1-(Dimethylamino)ethyl>phenol

methyl isocyanate

1-(3-methoxy)-phenylethanol

N,N-dimethyl-α-(m-methoxyphenyl)ethylamine