1-PHENOXYPHTHALAZINE

Base Information

• Chemical Name: 1-PHENOXYPHTHALAZINE
• CAS No.: 100537-30-2
• Molecular Formula: C₁₄H₁₀N₂O
• Molecular Weight: 222.246
• Mol file: 100537-30-2.mol

Synonyms:1-phenoxy-phthalazin;1-phenoxyphthalazine

Chemical Property of 1-PHENOXYPHTHALAZINE

Chemical Property:

• Vapor Pressure: 2.21E-07mmHg at 25°C
• Melting Point: 107-108°C
• Boiling Point: 435.6°Cat760mmHg
• Flash Point: 156.8°C
• PSA: 35.01000
• Density: 1.23g/cm³
• LogP: 3.42210
• Storage Temp.: Refrigerator
• Solubility.: Dichloromethane, Ethanol, Methanol

Purity/Quality:

98%min ^*data from raw suppliers

1-Phenoxyphthalazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1-Phenoxyphthalazine (cas# 100537-30-2) is a compound useful in organic synthesis. It is an intermediate in the synthesis of 1-Aminophthalazine (A627660)

Technology Process of 1-PHENOXYPHTHALAZINE

There total 2 articles about 1-PHENOXYPHTHALAZINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-chlorophthalazine (5784-45-2) + phenol (108-95-2,27073-41-2) → 1-Phenoxy-phthalazin (100537-30-2)

Guidance literature:

With potassium hydroxide;

Reference yield:

phthalazone (119-39-1) → 1-Phenoxy-phthalazin (100537-30-2)

Guidance literature:

Multi-step reaction with 2 steps

1: POCl₃

2: KOH

With potassium hydroxide; trichlorophosphate;

Reference yield:

1-Phenoxy-phthalazin (100537-30-2) + ammonium acetate (631-61-8,92206-38-7) → phthalazin-1-ylamine (19064-69-8)

Guidance literature:

upstream raw materials:

1-chlorophthalazine

phenol

phthalazone

Downstream raw materials:

phthalazin-1-ylamine

sulfanilic acid phthalazin-1-ylamide

N-acetyl-sulfanilic acid phthalazin-1-ylamide