19064-69-8Relevant articles and documents
PHTHALAZINE DERIVATIVES
-
, (2015/01/16)
Compounds of the formula (I), in which R1, X and n have the meanings indicated in Claim 1, are inhibitors of Tankyrase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous syst
Hydrazination of Pyridazines and Phthalazines
Counotte-Potman, A.,Plas, H. C. van der
, p. 1259 - 1261 (2007/10/02)
It is shown by 15N-labelling techniques that hydrazination of pyridazines partly occurs according to a reaction pathway, involving addition of the nucleophile (hydrazine), ring opening and ring closure (SN(ANRORC)-mechanism).It is also proved that phthalazines undergo hydrazination without ring opening (SN(AE)-mechanism).