2,5-Dicyclohexyl-4-methylphenol

Base Information

• Chemical Name: 2,5-Dicyclohexyl-4-methylphenol
• CAS No.: 20005-52-1
• Molecular Formula: C₁₉H₂₈O
• Molecular Weight: 272.431
• DSSTox Substance ID: DTXSID901303486
• Nikkaji Number: J1.139.472H
• Mol file: 20005-52-1.mol

Synonyms:2,5-Dicyclohexyl-4-methylphenol;SCHEMBL9785309;DTXSID901303486;20005-52-1

Chemical Property of 2,5-Dicyclohexyl-4-methylphenol

Chemical Property:

• XLogP3: 7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 272.214015512
• Heavy Atom Count: 20
• Complexity: 288

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1C2CCCCC2)O)C3CCCCC3

Technology Process of 2,5-Dicyclohexyl-4-methylphenol

There total 3 articles about 2,5-Dicyclohexyl-4-methylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

p-cresol (106-44-5) + cyclohexyl mesylate (16156-56-2) → 2,5-dicyclohexyl-4-methylphenol (20005-52-1) + 2,6-dicyclohexyl-4-methylphenol (7226-88-2) + 2-Cyclohexyl-4-methyl-phenol (1596-09-4)

Guidance literature:

With trifluorormethanesulfonic acid; at 80 ℃; for 0.5h;

DOI:10.1055/s-1999-3436

Reference yield: 5.2%

p-cresol (106-44-5) + cyclohexene (110-83-8) → 2,5-dicyclohexyl-4-methylphenol (20005-52-1) + 2,6-dicyclohexyl-4-methylphenol (7226-88-2) + 2-Cyclohexyl-4-methyl-phenol (1596-09-4)

Guidance literature:

With aluminium tris(p-methylphenoxide); at 200 ℃; for 11h; Further byproducts given;

Reference yield:

→ 2,5-dicyclohexyl-4-methylphenol (20005-52-1)

Guidance literature:

p-Kresol, Cyclohexanol, H3PO4;

upstream raw materials:

p-cresol

cyclohexene

cyclohexyl mesylate