7a-bromo-3-methyl-5-(phenylthio)-4,5,7,7a-tetrahydro-2H-furo[2,3-c]pyran-2-one

Base Information

Chemical Name:7a-bromo-3-methyl-5-(phenylthio)-4,5,7,7a-tetrahydro-2H-furo[2,3-c]pyran-2-one
CAS No.:1268671-29-9
Molecular Formula:C₁₄H₁₃BrO₃S
Molecular Weight:341.225
Hs Code.:

Synonyms:7a-bromo-3-methyl-5-(phenylthio)-4,5,7,7a-tetrahydro-2H-furo[2,3-c]pyran-2-one

Suppliers and Price of 7a-bromo-3-methyl-5-(phenylthio)-4,5,7,7a-tetrahydro-2H-furo[2,3-c]pyran-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 7a-bromo-3-methyl-5-(phenylthio)-4,5,7,7a-tetrahydro-2H-furo[2,3-c]pyran-2-one

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 7a-bromo-3-methyl-5-(phenylthio)-4,5,7,7a-tetrahydro-2H-furo[2,3-c]pyran-2-one

There total 9 articles about 7a-bromo-3-methyl-5-(phenylthio)-4,5,7,7a-tetrahydro-2H-furo[2,3-c]pyran-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1268671-30-2
cis-3-methyl-5-(phenylthio)-4,5,7,7a-tetrahydro-2H-furo[2,3-c]pyran-2-one

: 1268671-29-9
7a-bromo-3-methyl-5-(phenylthio)-4,5,7,7a-tetrahydro-2H-furo[2,3-c]pyran-2-one

Guidance literature:: cis-3-methyl-5-(phenylthio)-4,5,7,7a-tetrahydro-2H-furo[2,3-c]pyran-2-one; With N-Bromosuccinimide; In tetrachloromethane; for 0.25h; Reflux;

With 2,2'-azobis(isobutyronitrile);
DOI:10.1016/j.tet.2010.11.108

Reference yield: 82.0%

: 1268671-28-8
trans-3-methyl-5-(phenylthio)-4,5,7,7a-tetrahydro-2H-furo[2,3-c]pyran-2-one

: 1268671-29-9
7a-bromo-3-methyl-5-(phenylthio)-4,5,7,7a-tetrahydro-2H-furo[2,3-c]pyran-2-one

Guidance literature:: With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In tetrachloromethane;
DOI:10.1016/j.tet.2010.11.108

Reference yield:

: 87-72-9,608-45-7,608-46-8,608-47-9,2460-44-8,6748-95-4,6763-34-4,7261-26-9,7283-06-9,7283-07-0,7296-55-1,7296-56-2,7296-58-4,7296-59-5,7296-60-8,7296-61-9,7296-62-0,7322-30-7,10257-31-5,10257-32-6,10257-33-7,10257-34-8,10257-35-9,19982-83-3,20242-88-0,28697-53-2,36562-42-2,41546-41-2,89299-64-9,107655-34-5,115794-06-4,115794-07-5,130550-15-1,130606-21-2
D-Xylose

: 1268671-29-9
7a-bromo-3-methyl-5-(phenylthio)-4,5,7,7a-tetrahydro-2H-furo[2,3-c]pyran-2-one

Guidance literature:: Multi-step reaction with 8 steps

1: pyridine / 6 h / 20 °C

2: hydrogen bromide; acetic acid / dichloromethane / 3 h / 0 °C

3: copper(ll) sulfate pentahydrate; acetic acid; zinc / water / 2.5 h / 0 °C

4: methanol; sodium methylate / 4 h / 20 °C

5: dipyridinium dichromate; acetic acid / ethyl acetate / 16 h / 20 °C

6: caesium carbonate / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

7: Oxone; C₈H₆O₄^(2-)*Cu⁽²⁺⁾ / toluene / 6 h / 60 °C / Molecular sieve; Air atmosphere

8: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane

With pyridine; methanol; Oxone; N-Bromosuccinimide; dipyridinium dichromate; copper(ll) sulfate pentahydrate; 2,2'-azobis(isobutyronitrile); C₈H₆O₄^(2-)*Cu⁽²⁺⁾; hydrogen bromide; sodium methylate; caesium carbonate; acetic acid; zinc; In tetrahydrofuran; tetrachloromethane; dichloromethane; water; ethyl acetate; toluene; 6: Michael addition / 7: Wittig lactonization;
DOI:10.1016/j.tet.2010.11.108