4,5-dimethoxy-2-[3-oxo-3-phenylprop-1-en-1-yl]benzenesulfonylchloride

Base Information

• Chemical Name: 4,5-dimethoxy-2-[3-oxo-3-phenylprop-1-en-1-yl]benzenesulfonylchloride
• CAS No.: 294211-70-4
• Molecular Formula: C₁₇H₁₅ClO₅S
• Molecular Weight: 366.822
• Mol file: 294211-70-4.mol

Synonyms:4,5-dimethoxy-2-[3-oxo-3-phenylprop-1-en-1-yl]benzenesulfonylchloride

Chemical Property of 4,5-dimethoxy-2-[3-oxo-3-phenylprop-1-en-1-yl]benzenesulfonylchloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,5-dimethoxy-2-[3-oxo-3-phenylprop-1-en-1-yl]benzenesulfonylchloride

There total 3 articles about 4,5-dimethoxy-2-[3-oxo-3-phenylprop-1-en-1-yl]benzenesulfonylchloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.5%

3,4-dimethoxychalcone (53744-27-7,5416-71-7) → 4,5-dimethoxy-2-[3-oxo-3-phenylprop-1-en-1-yl]benzenesulfonylchloride (294211-70-4)

Guidance literature:

With chlorosulfonic acid; at 0 - 20 ℃; for 3h;

DOI:10.14233/ajchem.2013.14534

Reference yield:

acetophenone (98-86-2) → 4,5-dimethoxy-2-[3-oxo-3-phenylprop-1-en-1-yl]benzenesulfonylchloride (294211-70-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide / water; ethanol / 3 h / 20 °C / Heating

2: chlorosulfonic acid / 3 h / 0 - 20 °C

With chlorosulfonic acid; sodium hydroxide; In ethanol; water; 1: |Claisen-Schmidt Condensation;

DOI:10.14233/ajchem.2013.14534

Reference yield:

3,4-dimethoxy-benzaldehyde (120-14-9) → 4,5-dimethoxy-2-[3-oxo-3-phenylprop-1-en-1-yl]benzenesulfonylchloride (294211-70-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide / water; ethanol / 3 h / 20 °C / Heating

2: chlorosulfonic acid / 3 h / 0 - 20 °C

With chlorosulfonic acid; sodium hydroxide; In ethanol; water; 1: |Claisen-Schmidt Condensation;

DOI:10.14233/ajchem.2013.14534

upstream raw materials:

3,4-dimethoxy-benzaldehyde

acetophenone

3,4-dimethoxychalcone