monotetrahydropyranyl octa(ethylene glycol) monobenzyl ether

Base Information

• Chemical Name: monotetrahydropyranyl octa(ethylene glycol) monobenzyl ether
• CAS No.: 1611489-00-9
• Molecular Formula: C₂₈H₄₈O₁₀
• Molecular Weight: 544.683
• Mol file: 1611489-00-9.mol

Synonyms:monotetrahydropyranyl octa(ethylene glycol) monobenzyl ether

Chemical Property of monotetrahydropyranyl octa(ethylene glycol) monobenzyl ether

Chemical Property:

Purity/Quality:

99%+, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of monotetrahydropyranyl octa(ethylene glycol) monobenzyl ether

There total 9 articles about monotetrahydropyranyl octa(ethylene glycol) monobenzyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.3%

1-phenyl-2,5,8,11-tetraoxatridecan-13-ol (86259-87-2,1201808-31-2) + 2-(2-(2-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethyl 4-methylbenzenesulfonate (86259-89-4) → monotetrahydropyranyl octa(ethylene glycol) monobenzyl ether (1611489-00-9)

Guidance literature:

1-phenyl-2,5,8,11-tetraoxatridecan-13-ol; With sodium hydride; sodium iodide; In tetrahydrofuran; mineral oil; at 0 ℃; for 2h; Inert atmosphere;

2-(2-(2-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethyl 4-methylbenzenesulfonate; In tetrahydrofuran; mineral oil; for 12h; Reflux; Inert atmosphere;

DOI:10.1016/j.tetlet.2014.04.066

Reference yield:

Tetraethylene glycol (112-60-7) → monotetrahydropyranyl octa(ethylene glycol) monobenzyl ether (1611489-00-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 3,4-dihydro-2H-pyran; toluene-4-sulfonic acid / dichloromethane / 24 h / 20 °C / Inert atmosphere

1.2: 2 h / 0 °C / Inert atmosphere

2.1: sodium hydride; sodium iodide / tetrahydrofuran; mineral oil / 2 h / 0 °C / Inert atmosphere

2.2: 12 h / Reflux; Inert atmosphere

With 3,4-dihydro-2H-pyran; sodium hydride; toluene-4-sulfonic acid; sodium iodide; In tetrahydrofuran; dichloromethane; mineral oil;

DOI:10.1016/j.tetlet.2014.04.066

Reference yield:

3,4-dihydro-2H-pyran (110-87-2) → monotetrahydropyranyl octa(ethylene glycol) monobenzyl ether (1611489-00-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: toluene-4-sulfonic acid / tetrahydrofuran / 36 h / 20 °C / Inert atmosphere

2.1: sodium hydride; sodium iodide / tetrahydrofuran; mineral oil / 2 h / 0 °C / Inert atmosphere

2.2: 12 h / Reflux; Inert atmosphere

With sodium hydride; toluene-4-sulfonic acid; sodium iodide; In tetrahydrofuran; mineral oil;

DOI:10.1016/j.tetlet.2014.04.066

upstream raw materials:

Tetraethylene glycol

3,4-dihydro-2H-pyran

benzyl bromide

1-phenyl-2,5,8,11-tetraoxatridecan-13-ol

Downstream raw materials:

1-phenyl-2,5,8,11,14,17,20,23-octaoxapenta-cosan-25-ol

23-(tetrahydropyran-2-yloxy)-3,6,9,12,15,18,21-heptaoxatricosan-1-ol